دورية أكاديمية
An Overview of Different Vitamin D Compounds in the Setting of Adiposity
| العنوان: | An Overview of Different Vitamin D Compounds in the Setting of Adiposity |
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| المؤلفون: | Spyksma, Eva, Alexandridou, Anastasia, Mai, Knut, Volmer, Dietrich, Stokes, Caroline |
| المساهمون: | Fabbri, Andrea |
| بيانات النشر: | Humboldt-Universität zu Berlin |
| سنة النشر: | 2024 |
| المجموعة: | Open-Access-Publikationsserver der Humboldt-Universität: edoc-Server |
| مصطلحات موضوعية: | C3 epimer, inflammation, metabolic health, obesity, overweight, 25-hydroxyvitamin D, 610 Medizin und Gesundheit, ddc:610 |
| الوصف: | A large body of research shows an association between higher body weight and low vitamin D status, as assessed using serum 25-hydroxyvitamin D concentrations. Vitamin D can be metabolised in adipose tissue and has been reported to influence gene expression and modulate inflammation and adipose tissue metabolism in vitro. However, the exact metabolism of vitamin D in adipose tissue is currently unknown. White adipose tissue expresses the vitamin D receptor and hydroxylase enzymes, substantially involved in vitamin D metabolism and efficacy. The distribution and concentrations of the generated vitamin D compounds in adipose tissue, however, are largely unknown. Closing this knowledge gap could help to understand whether the different vitamin D compounds have specific health effects in the setting of adiposity. This review summarises the current evidence for a role of vitamin D in adipose tissue and discusses options to accurately measure vitamin D compounds in adipose tissue using liquid chromatography tandem mass spectrometry (LC/MS-MS). ; the German Research Foundation ; Peer Reviewed |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6643 |
| العلاقة: | http://edoc.hu-berlin.de/18452/29336Test; urn:nbn:de:kobv:11-110-18452/29336-4 |
| DOI: | 10.3390/nu16020231 |
| الإتاحة: | https://doi.org/10.3390/nu16020231Test http://edoc.hu-berlin.de/18452/29336Test https://nbn-resolving.org/urn:nbn:de:kobv:11-110-18452/29336-4Test |
| حقوق: | (CC BY 4.0) Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.53020D37 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20726643 |
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| DOI: | 10.3390/nu16020231 |