دورية أكاديمية
Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force.
| العنوان: | Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force. |
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| المؤلفون: | SOFFIETTI, Riccardo, B. G. Baumert, L. Bello, A. v. Deimling, H. Duffau, M. Frénay, W. Grisold, R. Grant, F. Graus, K. Hoang Xuan, M. Klein, B. Melin, J. Rees, T. Siegal, A. Smits, R. Stupp, W. Wick, E. F. of |
| المساهمون: | R. Soffietti, B. G. Baumert, L. Bello, A. v. Deimling, H. Duffau, M. Frénay, W. Grisold, R. Grant, F. Grau, K. Hoang-Xuan, M. Klein, B. Melin, J. Ree, T. Siegal, A. Smit, R. Stupp, W. Wick, E. F. of |
| سنة النشر: | 2010 |
| المجموعة: | Università degli studi di Torino: AperTo (Archivio Istituzionale ad Accesso Aperto) |
| مصطلحات موضوعية: | Advisory Committee, trends, Antineoplastic Protocol, standards, Cognition Disorder, drug therapy/etiology/surgery, Combined Modality Therapy, methods/standards, Europe, Evidence-Based Medicine, Glioma, radiotherapy/surgery/therapy, Humans, Neoplasm Metastasi, diagnosis/drug therapy/radiotherapy, Neoplasm Recurrence, Local, drug therapy/radiotherapy/surgery, Neurosurgical Procedure, Prognosis |
| الوصف: | WHO classification recognizes grade II astrocytomas, oligodendrogliomas and oligoastrocytomas. Conventional MRI is used for differential diagnosis, guiding surgery, planning radiotherapy and monitoring treatment response. Advanced imaging techniques can increase the diagnostic accuracy. Younger age, normal neurological examination, oligodendroglial histology and 1p loss are favorable prognostic factors. Prophylactic antiepileptic drugs are not useful, whilst there is no evidence that one drug is better than the others. Total/near total resection can improve seizure control, progression-free and overall survival, whilst reducing the risk of malignant transformation. Early post-operative radiotherapy improves progression-free but not overall survival. Low doses of radiation are as effective as high doses and better tolerated. Modern radiotherapy techniques reduce the risk of late cognitive deficits. Chemotherapy can be useful both at recurrence after radiotherapy and as initial treatment after surgery to delay the risk of late neurotoxicity from large-field radiotherapy. Neurocognitive deficits are frequent and can be caused by the tumor itself, tumor-related epilepsy, treatments and psychological distress. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/20718851; info:eu-repo/semantics/altIdentifier/wos/WOS:000280996800005; volume:17; firstpage:1124; lastpage:1133; numberofpages:9; journal:EUROPEAN JOURNAL OF NEUROLOGY; http://hdl.handle.net/2318/121624Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-77955817286 |
| DOI: | 10.1111/j.1468-1331.2010.03151.x |
| الإتاحة: | https://doi.org/10.1111/j.1468-1331.2010.03151.xTest http://hdl.handle.net/2318/121624Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.52E6EAE2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/j.1468-1331.2010.03151.x |
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