Chemical characterization of oligosaccharides in the milk of six species of New and Old world monkeys

التفاصيل البيبلوغرافية
العنوان: Chemical characterization of oligosaccharides in the milk of six species of New and Old world monkeys
المؤلفون: Goto, Kohta, Fukuda, Kenji, 福田, 健二, Senda, Akitsugu, Saito, Tadao, 齋藤, 忠夫, Kimura, Kazumasa, Glander, Kenneth E., Hinde, Katie, Dittus, Wolfgang, Milligan, Lauren A., Power, Michael L., Oftedal, Olav T., Urashima, Tadasu, 浦島, 匡
بيانات النشر: Springer
سنة النشر: 2010
المجموعة: Obihiro University: Obihiro Archives of Knowledge (OAK) / 帯広畜産大学学術情報リポジトリ
مصطلحات موضوعية: old world monkey, new world monkey, milk oligosaccharide, rhesus macaque, toque macaque, baboon, capuchin, mantled howler, squirrel monkey, N-glycolylneuraminic acid
الوصف: application/pdf ; Human and great ape milks contain a diverse array of milk oligosaccharides, but little is known about the milk oligosaccharides of other primates, and how they differ among taxa. Neutral and acidic oligosaccharides were isolated from the milk of three species of Old World or catarrhine monkeys (Cercopithecidae: rhesus macaque (Macaca mulatta), toque macaque (Macaca sinica) and Hamadryas baboon (Papio hamadryas)) and three of New World or platyrrhine monkeys (Cebidae: tufted capuchin (Cebus apella)and Bolivian squirrel monkey (Saimiri boliviensis); Atelidae: mantled howler (Alouatta palliata)). The milks of these species contained 6-8% total sugar, most of which was lactose: the estimated ratio of oligosaccharides to lactose in Old World monkeys (1:4 to 1:6) was greater than in New World monkeys (1:12 to 1:23). The chemical structures of the oligosaccharides were determined mainly by 1H-NMR spectroscopy. Oligosaccharides containing the type II unit (Gal(β1-4)GlcNAc) were found in the milk of the rhesus macaque, toque macaque, Hamadryas baboon and tufted capuchin, but oligosaccharides containing the type I unit (Gal(β1-3)GlcNAc), which have been found in human and many great ape milks, were absent from the milk of all species studied. Oligosaccharides containing Lewis x (Gal(β1-4)[Fuc(α1-3)]GlcNAc) and 3-fucosyl lactose (Gal(β1-4)[Fuc(α1-3)]Glc) were found in the milk of the three cercopithecid monkey species, while 2-fucosyl lactose (Fuc(α1-2)Gal(β1-4)Glc) was absent from all species studied. All of these milks contained acidic oligosaccharides that had N-acetylneuraminic acid as part of their structures, but did not contain oligosaccharides that had N-glycolylneuraminic acid, in contrast to the milk or colostrum of great apes which contain both types of acidic oligosaccharides. Two GalNAc-containing oligosaccharides, lactose 3’-O-sulfate and lacto-N-novopentaose I (Gal(β1-3)[Gal(β1-4)GlcNAc(β1-6)]Gal(β1-4)Glc) were found only in the milk of rhesus macaque, hamadryas baboon and tufted capuchin, ...
نوع الوثيقة: other/unknown material
وصف الملف: application/pdf
اللغة: English
تدمد: 02820080
العلاقة: Glycoconjugate Journal; 27; 703; 715; AA10451191; https://obihiro.repo.nii.ac.jp/record/731/files/GLYC594.pdfTest
الإتاحة: https://obihiro.repo.nii.ac.jp/record/731/files/GLYC594.pdfTest
حقوق: Springer
رقم الانضمام: edsbas.50C127EB
قاعدة البيانات: BASE