دورية أكاديمية
Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization
| العنوان: | Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization |
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| المؤلفون: | Louis, Véronique Leh, Despons, Laurence, Friedrich, Anne, Martin, Tiphaine, Durrens, Pascal, Casaregola, Serge, Neuvéglise, Cécile, Fairhead, Cécile, Marck, Christian, Cruz, José A., Straub, Marie-Laure, Kugler, Valérie, Sacerdot, Christine, Uzunov, Zlatyo, Thierry, Agnès, Weiss, Stéphanie, Bleykasten, Claudine, de Montigny, Jacky, Jacques, Noémie, Jung, Paul, Lemaire, Marc, Mallet, Sandrine, Morel, Guillaume, Richard, Guy-Franck, Sarkar, Anasua, Savel, Guilhem, Schacherer, Joseph, Seret, Marie-Line, Talla, Emmanuel, Samson, Gaëlle, Jubin, Claire, Poulain, Julie, Vacherie, Benoit, Barbe, Valérie, Pelletier, Eric, Sherman, David J., Westhof, Eric, Weissenbach, Jean, Baret, Philippe V., Wincker, Patrick, Gaillardin, Claude, Dujon, Bernard, Souciet, Jean-Luc |
| المساهمون: | Université de Strasbourg (UNISTRA), Models and Algorithms for the Genome ( MAGNOME), Inria Bordeaux - Sud-Ouest, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, AgroParisTech, Institut de génétique et microbiologie Orsay (IGM), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie et de Technologies de Saclay (IBITECS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Architecture et Réactivité de l'ARN (ARN), Institut de biologie moléculaire et cellulaire (IBMC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Génétique moléculaire, génomique, microbiologie (GMGM), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Biologie systémique - Systems Biology, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Génétique moléculaire des levures (YMG), Microbiologie, adaptation et pathogénie (MAP), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Génétique Moléculaire des Levures, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Bordelais de Recherche en Informatique (LaBRI), Université de Bordeaux (UB)-École Nationale Supérieure d'Électronique, Informatique et Radiocommunications de Bordeaux (ENSEIRB)-Centre National de la Recherche Scientifique (CNRS), Earth and Life Institute Louvain-La-Neuve (ELI), Université Catholique de Louvain = Catholic University of Louvain (UCL), Laboratoire de chimie bactérienne (LCB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Genoscope - Centre national de séquençage Evry (GENOSCOPE), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut de Génomique d'Evry (IG), Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Génomique métabolique (UMR 8030), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS), This work was supported in part by funding from the Consortium National de Recherche en Génomique (CNRG) to Génoscope, from CNRS (GDR 2354, Génolevures), ANR (ANR-05-BLAN-0331, GENARISE). The computer framework was supported by the funding of the University of Bordeaux 1, the Aquitaine Région in the program “Génotypage et Génomique Comparée,” and the ACI IMPBIO “Génolevures En Ligne.”We thank the System and Network Administration team in LaBRI for excellent help and advice. J.A.C. is supported by the PhD Program in Computational Biology of the Instituto Gulbenkian de Ciência, Portugal (sponsored by Fundação Calouste Gulbenkian, Siemens SA, and Fundação para a Ciência e Tecnologia, SFRH/BD/33528/2008), ANR-05-BLAN-0331,GENARISE,How do genes arise ? Lessons and questions from the evolution of yeast genomes.(2005) |
| المصدر: | ISSN: 2160-1836 ; G3 ; https://hal.science/hal-00679348Test ; G3, 2012, 2 (2), pp.299 - 311. ⟨10.1534/g3.111.000745⟩. |
| بيانات النشر: | HAL CCSD Genetics Society of America |
| سنة النشر: | 2012 |
| المجموعة: | Institut Pasteur: HAL |
| مصطلحات موضوعية: | HEMIASCOMYCETOUS YEASTS, CANDIDA-ALBICANS, DNA-SEQUENCES, GENE, GLYCEROL, HALOTOLERANT, SPECIATION, SACCHAROMYCES-CEREVISIAE, NUCLEOLAR DOMINANCE, EVOLUTION, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN] |
| الوصف: | the Consortium National de Recherche en Génomique (CNRG) to Génoscope, CNRS (GDR 2354, Génolevures), The computer framework was supported by the funding of the University of Bordeaux 1, the Aquitaine Région in the program "Génotypage et Génomique Comparée," and the ACI IMPBIO "Génolevures En Ligne." ; International audience ; Polyploidization is an important process in the evolution of eukaryotic genomes, but ensuing molecular mechanisms remain to be clarified. Autopolyploidization or whole-genome duplication events frequently are resolved in resulting lineages by the loss of single genes from most duplicated pairs, causing transient gene dosage imbalance and accelerating speciation through meiotic infertility. Allopolyploidization or formation of interspecies hybrids raises the problem of genetic incompatibility (Bateson-Dobzhansky-Muller effect) and may be resolved by the accumulation of mutational changes in resulting lineages. In this article, we show that an osmotolerant yeast species, Pichia sorbitophila, recently isolated in a concentrated sorbitol solution in industry, illustrates this last situation. Its genome is a mosaic of homologous and homeologous chromosomes, or parts thereof, that corresponds to a recently formed hybrid in the process of evolution. The respective parental contributions to this genome were characterized using existing variations in GC content. The genomic changes that occurred during the short period since hybrid formation were identified (e.g., loss of heterozygosity, unilateral loss of rDNA, reciprocal exchange) and distinguished from those undergone by the two parental genomes after separation from their common ancestor (i.e., NUMT (NUclear sequences of MiTochondrial origin) insertions, gene acquisitions, gene location movements, reciprocal translocation). We found that the physiological characteristics of this new yeast species are determined by specific but unequal contributions of its two parents, one of which could be identified as very closely related to an extant Pichia ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/22384408; hal-00679348; https://hal.science/hal-00679348Test; https://hal.science/hal-00679348/documentTest; https://hal.science/hal-00679348/file/299.full.pdfTest; PRODINRA: 218228; PUBMED: 22384408; WOS: 000312411000017 |
| DOI: | 10.1534/g3.111.000745 |
| الإتاحة: | https://doi.org/10.1534/g3.111.000745Test https://hal.science/hal-00679348Test https://hal.science/hal-00679348/documentTest https://hal.science/hal-00679348/file/299.full.pdfTest |
| حقوق: | http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.50972C12 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1534/g3.111.000745 |
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