دورية أكاديمية
Changes in Health-Related Quality of Life following Surgery in Patients with High-Grade Extremity Soft-Tissue Sarcoma:A Prospective Longitudinal Study
| العنوان: | Changes in Health-Related Quality of Life following Surgery in Patients with High-Grade Extremity Soft-Tissue Sarcoma:A Prospective Longitudinal Study |
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| المؤلفون: | Kruiswijk, Anouk A., van de Sande, Michiel A. J., Verhoef, Cornelis, Schrage, Yvonne M., Haas, Rick L., Bemelmans, Marc H. A., van Ginkel, Robert J., Bonenkamp, Johannes J., Witkamp, Arjen J., van den Akker-van Marle, M. Elske, Marang-van de Mheen, Perla J., van Bodegom-Vos, Leti |
| المصدر: | Kruiswijk , A A , van de Sande , M A J , Verhoef , C , Schrage , Y M , Haas , R L , Bemelmans , M H A , van Ginkel , R J , Bonenkamp , J J , Witkamp , A J , van den Akker-van Marle , M E , Marang-van de Mheen , P J & van Bodegom-Vos , L 2024 , ' Changes in Health-Related Quality of Life following Surgery in Patients with High-Grade Extremity Soft-Tissue Sarcoma : A Prospective Longitudinal Study ' , Cancers , vol. 16 , no. .... |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being |
| الوصف: | Introduction: Changes in health-related quality of life (HRQoL) during the diagnostic and treatment trajectory of high-grade extremity soft-tissue sarcoma (eSTS) has rarely been investigated for adults (18–65 y) and the elderly (aged ≥65 y), despite a potential variation in challenges from diverse levels of physical, social, or work-related activities. This study assesses HRQoL from time of diagnosis to one year thereafter among adults and the elderly with eSTS. Methods: HRQoL of participants from the VALUE-PERSARC trial (n = 97) was assessed at diagnosis and 3, 6 and 12 months thereafter, utilizing the PROMIS Global Health (GH), PROMIS Physical Function (PF) and EQ-5D-5L. Results: Over time, similar patterns were observed in all HRQoL measures, i.e., lower HRQoL scores than the Dutch population at baseline (PROMIS-PF:46.8, PROMIS GH-Mental:47.3, GH-Physical:46.2, EQ-5D-5L:0.76, EQ-VAS:72.6), a decrease at 3 months, followed by an upward trend to reach similar scores as the general population at 12 months (PROMIS-PF:49.9, PROMIS GH-Physical:50.1, EQ-5D-5L:0.84, EQ-VAS:81.5), except for the PROMIS GH-Mental (47.5), where scores remained lower than the general population mean (T = 50). Except for the PROMIS-PF, no age-related differences were observed. Conclusions: On average, eSTS patients recover well physically from surgery, yet the mental component demonstrates no progression, irrespective of age. These results underscore the importance of comprehensive care addressing both physical and mental health. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://pure.eur.nl/en/publications/a9763c0a-feb9-4527-bf11-1140294b7630Test |
| DOI: | 10.3390/cancers16030547 |
| الإتاحة: | https://doi.org/10.3390/cancers16030547Test https://pure.eur.nl/en/publications/a9763c0a-feb9-4527-bf11-1140294b7630Test https://pure.eur.nl/ws/files/136773780/cancers-16-00547-v2.pdfTest http://www.scopus.com/inward/record.url?scp=85185251517&partnerID=8YFLogxKTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.506CEAF4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/cancers16030547 |
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