دورية أكاديمية
Magnetic resonance imaging-based scores of small vessel diseases: Associations with intracerebral haemorrhage location.
| العنوان: | Magnetic resonance imaging-based scores of small vessel diseases: Associations with intracerebral haemorrhage location. |
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| المؤلفون: | Schwarz, Ghil, Banerjee, Gargi, Hostettler, Isabel Charlotte, Ambler, Gareth, Seiffge, David J, Brookes, Tenzin S, Wilson, Duncan, Cohen, Hannah, Yousry, Tarek, Salman, Rustam Al-Shahi, Lip, Gregory Y H, Brown, Martin M, Muir, Keith W, Houlden, Henry, Jäger, Rolf, Werring, David J, Staals, Julie |
| المصدر: | Schwarz, Ghil; Banerjee, Gargi; Hostettler, Isabel Charlotte; Ambler, Gareth; Seiffge, David J; Brookes, Tenzin S; Wilson, Duncan; Cohen, Hannah; Yousry, Tarek; Salman, Rustam Al-Shahi; Lip, Gregory Y H; Brown, Martin M; Muir, Keith W; Houlden, Henry; Jäger, Rolf; Werring, David J; Staals, Julie (2022). Magnetic resonance imaging-based scores of small vessel diseases: Associations with intracerebral haemorrhage location. Journal of the neurological sciences, 434, p. 120165. Elsevier 10.1016/j.jns.2022.120165 |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2022 |
| المجموعة: | BORIS (Bern Open Repository and Information System, University of Bern) |
| مصطلحات موضوعية: | 610 Medicine & health |
| الوصف: | INTRODUCTION Total small vessel disease (SVD) score and cerebral amyloid angiopathy (CAA) score are magnetic resonance imaging-based composite scores built to preferentially capture deep perforator arteriopathy-related and CAA-related SVD burden, respectively. Non-lobar intracerebral haemorrhage (ICH) is related to deep perforator arteriopathy, while lobar ICH can be associated with deep perforator arteriopathy or CAA; however, the associations between ICH location and these scores are not established. METHODS In this post-hoc analysis from a prospective cohort study, we included 153 spontaneous non-cerebellar ICH patients. Wald test, univariable and multivariable logistic regression analysis were performed to investigate the association between each score (and individual score components) and ICH location. RESULTS Total SVD score was associated with non-lobar ICH location (Wald test: unadjusted, p = 0.017; adjusted, p = 0.003); however, no individual component of total SVD score was significantly associated with non-lobar ICH. CAA score was not significantly associated with lobar location (Wald test: unadjusted, p = 0.056; adjusted, p = 0.126); cortical superficial siderosis (OR 8.85 [95%CI 1.23-63.65], p = 0.030) and ≥ 2 strictly lobar microbleeds (OR 1.63 [95%CI 1.04-2.55], p = 0.035) were related with lobar ICH location, while white matter hyperintensities showed an inverse relation (OR 0.53 [95%CI 0.26-1.08; p = 0.081]). CONCLUSIONS Total SVD score was associated with non-lobar ICH location. The lack of significant association between CAA score and lobar ICH may in part be due to the mixed aetiology of lobar ICH, and to the inclusion of white matter hyperintensities, a non-specific marker of SVD type, in the CAA score. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://boris.unibe.ch/174403Test/ |
| الإتاحة: | https://doi.org/10.1016/j.jns.2022.120165Test https://boris.unibe.ch/174403/1/Schwarz__2022__Magnetic_resonance_imaging_based_scores_of_small_vessel_diseases.pdfTest https://boris.unibe.ch/174403Test/ |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.4E94209D |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |