دورية أكاديمية
Prevalence of SARS-CoV-2-specific antibodies in a sample of the Lithuanian population-based study in Spring 2023 /
| العنوان: | Prevalence of SARS-CoV-2-specific antibodies in a sample of the Lithuanian population-based study in Spring 2023 / |
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| المؤلفون: | Simanavičius, Martynas, Kučinskaitė-Kodzė, Indrė, Kaselienė, Snieguolė, Sauliūnė, Skirmantė, Gudas, Dainius, Jančorienė, Ligita, Jasinskienė, Rūta, Vitkauskienė, Astra, Žūtautienė, Rasa, Žvirblienė, Aurelija, Stankūnas, Mindaugas |
| المصدر: | Heliyon., Cambridge, MA : Cell Press, 2024, vol. 10, iss. 8, art. no. e29343, p. [1-11]. ; ISSN 2405-8440 |
| سنة النشر: | 2024 |
| المجموعة: | Vilnius University Virtual Library (VU VL) / Vilniaus universitetas virtuali biblioteka |
| مصطلحات موضوعية: | COVID-19, SARS-CoV-2, Lithuania, Anti-N IgG, Seroprevalence |
| الوصف: | Objectives: Despite positive trends in SARS-CoV-2 epidemiology, seroprevalence surveys remain an important tool for estimating the magnitude of the COVID-19 pandemic. This study aimed to investigate the prevalence of IgG antibodies against SARS-CoV-2 nucleocapsid (N) and spike (S) proteins in a sample of the Lithuanian population (N = 517) and evaluate how the pattern of seropositivity correlates with the levels of SARS-CoV-2 infection and vaccination. Methods: Study participants (aged 18–88 years) filled in the questionnaire self-reporting their demographic-social variables, health status, and SARS-CoV-2-related status. The anti-S and anti-N IgG levels were estimated using a microarray ELISA test. Results: After several pandemic waves and vaccination campaign, the seroprevalence of SARSCoV- 2-specific IgG in the analyzed sample was 97.87 % by March–May 2023. We determined the 96.91 % prevalence of anti-S and 58.03 % prevalence of anti-N IgG. The majority of study participants (71.18 %) had hybrid immunity induced by vaccination and SARS-CoV-2 infection. 20.3 % of study participants were anti-N IgG positive without reporting any previous symptoms or a positive SARS-CoV-2 test. A decline of anti-N IgG positivity within 9 months after infection was observed. Conclusions: This study demonstrates high total seroprevalence in March–May 2023 in all age groups indicating a widely established humoral immunity against SARS-CoV-2 in Lithuania. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://epublications.vu.lt/object/elaba:194032169/194032169.pdfTest; https://repository.vu.lt/VU:ELABAPDB194032169&prefLang=en_USTest |
| الإتاحة: | https://doi.org/10.1016/j.heliyon.2024.e29343Test https://repository.vu.lt/VU:ELABAPDB194032169&prefLang=en_USTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.4E70C621 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |