دورية أكاديمية
The Role of Surveillance Inspections in Reducing False-Positives of SARS-CoV-2 Omicron Variants during the COVID-19 Epidemic
| العنوان: | The Role of Surveillance Inspections in Reducing False-Positives of SARS-CoV-2 Omicron Variants during the COVID-19 Epidemic |
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| المؤلفون: | Li-Li Liu, Yu-Hong Zheng, You-Quan Zhang, Jin-Piao Lin, Zhi-Lin Luo, Liu-Min Yu, Shi-Hua Gao, Falin Chen |
| المصدر: | Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2023 (2023) |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2023 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502 |
| الوصف: | Objective. This study aims to assess the effectiveness of surveillance inspections conducted by the provincial health committee in Quanzhou city during a COVID-19 outbreak in reducing false-positive results in SARS-CoV-2 RT-PCR assays. Method. The team conducted on-site inspections of laboratories that participated in mass screening, recording any violations of rules. Results. The positive cases in five rounds of mass screening were 23, 173, and 4 in Licheng District, Fengze District, and Luojang District, respectively. The false-positive rates in the five rounds of mass screening were 0.0099%, 0.0063%, 0.0018%, 0.0006%, and 0%, respectively. The study also recorded that the number of violations in the seven selected laboratories was 36, 68, 69, 42, 60, 54 and 47. The corresponding false-positive rates were 0.0012%, 0.0060%, 0.0082%, 0.0032%, 0.0060%, 0.0027%, and 0.0021%, respectively. The study found a positive correlation between false-positive rates and the number of violations (r = 0.905, P=0.005), and an inverse correlation between false-positive rates and the frequency of surveillance inspections (r = −0.950, P<0.001). Conclusion. Daily surveillance inspection in laboratories can remind laboratories to strictly comply with standard procedures, focus on laboratory quality control, and reduce the occurrence of false-positive cases in SARS-CoV-2 nucleic acid tests to some extent. This study recommends that government decision-making departments establish policies and arrange experts to conduct daily surveillance inspections to improve laboratory quality control. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1918-1493 |
| العلاقة: | http://dx.doi.org/10.1155/2023/8508975Test; https://doaj.org/toc/1918-1493Test; https://doaj.org/article/589c011454b447198d2e59d905cff805Test |
| DOI: | 10.1155/2023/8508975 |
| الإتاحة: | https://doi.org/10.1155/2023/8508975Test https://doaj.org/article/589c011454b447198d2e59d905cff805Test |
| رقم الانضمام: | edsbas.4DAC8865 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 19181493 |
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| DOI: | 10.1155/2023/8508975 |