دورية أكاديمية
Ethnic differences in COVID-19 mortality in the second and third waves of the pandemic in England during the vaccine roll-out: a retrospective, population-based cohort study
| العنوان: | Ethnic differences in COVID-19 mortality in the second and third waves of the pandemic in England during the vaccine roll-out: a retrospective, population-based cohort study |
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| المؤلفون: | Bosworth, Matthew L, Ahmed, Tamanna, Larsen, Tim, Lorenzi, Luke, Morgan, Jasper, Ali, Raghib, Goldblatt, Peter, Islam, Nazrul, Khunti, Kamlesh, Raleigh, Veena, Ayoubkhani, Daniel, Bannister, Neil, Glickman, Myer, Nafilyan, Vahe |
| سنة النشر: | 2023 |
| المجموعة: | University of Southampton: e-Prints Soton |
| الوصف: | Background: Ethnic minority groups in England have been disproportionately affected by the COVID-19 pandemic and have lower vaccination rates than the White British population. We examined whether ethnic differences in COVID-19 mortality in England have continued since the vaccine rollout and to what extent differences in vaccination rates contributed to excess COVID-19 mortality after accounting for other risk factors. Methods: We conducted a retrospective, population-based cohort study of 28.8 million adults aged 30–100 years in England. Self-reported ethnicity was obtained from the 2011 Census. The outcome was death involving COVID-19 during the second (8 December 2020 to 12 June 2021) and third wave (13 June 2021 to 1 December 2021). We calculated hazard ratios (HRs) for death involving COVID-19, sequentially adjusting for age, residence type, geographical factors, sociodemographic characteristics, pre-pandemic health, and vaccination status. Results: Age-adjusted HRs of death involving COVID-19 were elevated for most ethnic minority groups during both waves, particularly for groups with lowest vaccination rates (Bangladeshi, Pakistani, Black African, and Black Caribbean). HRs were attenuated after adjusting for geographical factors, sociodemographic characteristics, and pre-pandemic health. Further adjusting for vaccination status substantially reduced residual HRs for Black African, Black Caribbean, and Pakistani groups in the third wave. Fully adjusted HRs only remained elevated for the Bangladeshi group (men: 2.19 [95% CI 1.72–2.78]; women: 2.12 [1.58–2.86]) and Pakistani men (1.24 [1.06–1.46]). Conclusions: Lower COVID-19 vaccination uptake in several ethnic minority groups may drive some of the differences in COVID-19 mortality compared to White British. Public health strategies to increase vaccination uptake in ethnic minority groups would help reduce inequalities in COVID-19 mortality, which have remained substantial since the start of the vaccination campaign. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://eprints.soton.ac.uk/470499/1/2022.02.14.22270940v1.full.pdfTest; https://eprints.soton.ac.uk/470499/2/s12916_022_02704_7_1_.pdfTest; Bosworth, Matthew L, Ahmed, Tamanna, Larsen, Tim and Islam, Nazrul , et al. (2023) Ethnic differences in COVID-19 mortality in the second and third waves of the pandemic in England during the vaccine roll-out: a retrospective, population-based cohort study. BMC Medicine, 21 (1), [13]. (doi:10.1101/2022.02.14.22270940 ). |
| الإتاحة: | https://doi.org/10.1101/2022.02.14.22270940Test https://eprints.soton.ac.uk/470499Test/ https://eprints.soton.ac.uk/470499/1/2022.02.14.22270940v1.full.pdfTest https://eprints.soton.ac.uk/470499/2/s12916_022_02704_7_1_.pdfTest |
| حقوق: | cc_by_nc_nd_4 ; cc_by_4 |
| رقم الانضمام: | edsbas.4D99A07D |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |