دورية أكاديمية
Major lower extremity amputations – risk of re-amputation, time to re-amputation, and risk factors: a nationwide cohort study from Denmark
| العنوان: | Major lower extremity amputations – risk of re-amputation, time to re-amputation, and risk factors: a nationwide cohort study from Denmark |
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| المؤلفون: | Brix, Anna Trier Heiberg, Rubin, Katrine Hass, Nymark, Tine, Schmal, Hagen, Lindberg-Larsen, Martin |
| المصدر: | Acta orthopaedica. - 95 (2024) , 86-91, ISSN: 1745-3682 |
| سنة النشر: | 2024 |
| المجموعة: | University of Freiburg: FreiDok |
| الوصف: | Background and purpose: Re-amputation after lower extremity amputation is frequent. The primary aim of our study was to investigate cumulative re-amputation risk after transtibial amputation (TTA), knee disarticulation (KD), and transfemoral amputation (TFA) and secondarily to investigate time to re-amputation, and risk factors. Methods: This observational cohort study was based on data from the Danish Nationwide Health registers. The population included first-time major lower extremity amputations (MLEA) performed in patients ≥ 50 years between 2010 and 2021. Both left and right sided MLEA from the same patient were included as index procedures. Results: 11,743 index MLEAs on 10,052 patients were included. The overall cumulative risks for re-amputation were 29% (95% confidence interval [CI] 27–30), 30% (CI 26–35), and 11% (CI 10–12) for TTA, KD, and TFA, respectively. 58% of re-amputations were performed within 30 days after index MLEA. Risk factors for re-amputation within 30 days were dyslipidemia (hazard ratio [HR] 1.2, CI 1.0–1.3), renal insufficiency (HR 1.2, CI 1.1–1.4), and prior vascular surgery (HR 1.3, CI 1.2–1.5). Conclusion: The risk of re-amputation was more than twice as high after TTA (29%) and KD (30%) compared with TFA (11%). Most re-amputations were conducted within 30 days of the index MLEA. Dyslipidemia, renal insufficiency, and prior vascular surgery were associated with higher risk of re-amputation. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | |
| اللغة: | English |
| العلاقة: | https://freidok.uni-freiburg.de/data/246701Test |
| DOI: | 10.2340/17453674.2024.39963 |
| الإتاحة: | https://doi.org/10.2340/17453674.2024.39963Test https://freidok.uni-freiburg.de/data/246701Test https://nbn-resolving.org/urn:nbn:de:bsz:25-freidok-2467017Test https://freidok.uni-freiburg.de/dnb/download/246701Test |
| حقوق: | free |
| رقم الانضمام: | edsbas.4D7C89E8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.2340/17453674.2024.39963 |
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