التفاصيل البيبلوغرافية
| العنوان: |
Prevalence, risk factors and outcome of Mycoplasma pneumoniae infection among children in Uganda: a prospective study |
| المؤلفون: |
Rebecca Nantanda (491008), Freddie Bwanga (221684), Irene Najjingo (492194), Grace Ndeezi (491009), James K Tumwine (11661522) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Medicine, Biotechnology, Immunology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Mycoplasma pneumonia, atypical pneumonia, prevalence, outcome |
| الوصف: |
Atypical bacteria cause 10–40% of all childhood pneumonia. Data on the burden of atypical pneumonia in sub-Saharan Africa are limited. : To determine the prevalence, associated factors, and outcome of Mycoplasma pneumoniae infection in children with respiratory symptoms at Mulago National Referral Hospital, Kampala. : Children aged 2 months to 12 years with cough and/or difficult breathing and fast breathing were recruited. A clinical history and physical examination were undertaken. Blood samples for Mycoplasma pneumoniae IgM antibodies were taken at enrolment and Day 21 and induced sputum for DNA-PCR. Admitted participants were followed for a maximum of 7 days or until discharge or death, whichever came first. : A total of 385 children were enrolled, and, of these, 368 (95.6%) were <5 years. Overall, 60/385 (15.6%) participants tested positive for M. pneumoniae IgM and/or DNA-PCR. Of these, 56/60 (93.3%) were <5 years of age. Wheezing was present in 21/60 (35.0%) of the children with atypical pneumonia and in 128/325 (39.4%) with typical pneumonia. The factors associated with M. pneumonia were female sex (AOR 1.94, 95% CI 1.22–3.08, p < 0.001), age ≥12 months (AOR 2.73, 95% CI 1.53–4.87, p = 0.01) and a history of prematurity (AOR 2.07, 95% CI 1.23–3.49, p = 0.01). Mortality was 17/352 (4.8%) and, of these, 4/17 (23.5%) had M. pneumonia . : M. pneumonia is common in young children , especially females above 2 years and those with history of prematurity. It presents with severe symptoms. The results of the study highlight the importance of considering atypical bacteria in under-5s with the symptoms of pneumonia. |
| نوع الوثيقة: |
dataset |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/dataset/Prevalence_risk_factors_and_outcome_of_Mycoplasma_pneumoniae_infection_among_children_in_Uganda_a_prospective_study/16949838Test |
| DOI: |
10.6084/m9.figshare.16949838.v1 |
| الإتاحة: |
https://doi.org/10.6084/m9.figshare.16949838.v1Test |
| حقوق: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.4BA285B7 |
| قاعدة البيانات: |
BASE |
