دورية أكاديمية
Effects of mnemonic load on cortical activity during visual working memory: Linking ongoing brain activity with evoked responses
| العنوان: | Effects of mnemonic load on cortical activity during visual working memory: Linking ongoing brain activity with evoked responses |
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| المؤلفون: | Boonstra, TW, Powell, TY, Mehrkanoon, S, Breakspear, M |
| المصدر: | urn:ISSN:0167-8760 ; urn:ISSN:1872-7697 ; International Journal of Psychophysiology, 89, 3, 409-418 |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2013 |
| المجموعة: | UNSW Sydney (The University of New South Wales): UNSWorks |
| مصطلحات موضوعية: | Behavioral and Social Science, Neurosciences, Basic Behavioral and Social Science, Eye Disease and Disorders of Vision, Clinical Research, Brain Disorders, 1.1 Normal biological development and functioning, 1 Underpinning research, 2 Aetiology, 2.1 Biological and endogenous factors, Neurological, Adult, Brain Mapping, Cerebral Cortex, Electroencephalography, Evoked Potentials, Female, Humans, Male, Memory, Short-Term, Multivariate Analysis, Photic Stimulation, Reaction Time, Time Factors, Young Adult, Alpha oscillations, Event-related potential, Partial least squares, Theta oscillations |
| الوصف: | The mechanisms generating task-locked changes in cortical potentials remain poorly understood, despite a wealth of research. It has recently been proposed that ongoing brain oscillations are not symmetric, so that task-related amplitude modulations generate a baseline shift that does not average out, leading to slow event-related potentials. We test this hypothesis using multivariate methods to formally assess the co-variation between task-related evoked potentials and spectral changes in scalp EEG during a visual working memory task, which is known to elicit both evoked and sustained cortical activities across broadly distributed cortical regions. 64-channel EEG data were acquired from eight healthy human subjects who completed a visuo-spatial associative working memory task as memory load was parametrically increased from easy to hard. As anticipated, evoked activity showed a complex but robust spatio-temporal waveform maximally expressed bilaterally in the parieto-occipital and anterior midline regions, showing robust effects of memory load that were specific to the stage of the working memory trial. Similarly, memory load was associated with robust spectral changes in the theta and alpha range, throughout encoding in posterior regions and through maintenance and retrieval in anterior regions, consistent with the additional resources required for decision making in prefrontal cortex. Analysis of the relationship between event-related changes in slow potentials and cortical rhythms, using partial least squares, is indeed consistent with the notion that the former make a causal contribution to the latter. © 2013 Elsevier B.V. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | http://hdl.handle.net/1959.4/unsworks_49700Test; https://unsworks.unsw.edu.au/bitstreams/0be94799-91db-469d-a8d6-a81c01735db5/downloadTest; https://doi.org/10.1016/j.ijpsycho.2013.04.001Test |
| DOI: | 10.1016/j.ijpsycho.2013.04.001 |
| الإتاحة: | https://doi.org/10.1016/j.ijpsycho.2013.04.001Test http://hdl.handle.net/1959.4/unsworks_49700Test https://unsworks.unsw.edu.au/bitstreams/0be94799-91db-469d-a8d6-a81c01735db5/downloadTest |
| حقوق: | open access ; https://purl.org/coar/access_right/c_abf2Test ; CC-BY-NC-ND ; https://creativecommons.org/licenses/by-nc-nd/4.0Test/ ; free_to_read |
| رقم الانضمام: | edsbas.4B4F90D3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.ijpsycho.2013.04.001 |
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