دورية أكاديمية

A National Consensus Survey for Current Practice in Brain Tumor Management I: Antiepileptic Drug and Steroid Usage

التفاصيل البيبلوغرافية
العنوان: A National Consensus Survey for Current Practice in Brain Tumor Management I: Antiepileptic Drug and Steroid Usage
المؤلفون: Kim, Sung Kwon, Moon, Jangsup, Cho, Jin Mo, Kim, Kyung Hwan, Kim, Se Hoon, Kim, Young Il, Kim, Young Zoon, Kim, Ho Sung, Dho, Yun-Sik, Park, Jae-Sung, Park, Ji Eun, Seo, Youngbeom, Sung, Kyoung Su, Song, Jin Ho, Wee, Chan Woo, Yoon, Wan-Soo, Yoon, Hong In, Lee, Se-Hoon, Lim, Do Hoon, Im, Jung Ho, Chang, Jong Hee, Han, Myung-Hoon, Hong, Je Beom, Hwang, Kihwan, Park, Chul-Kee, Lee, Youn Soo, Gwak, Ho-Shin
المصدر: Brain Tumor Res Treat
بيانات النشر: The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology; The Korean Society for Pediatric Neuro-Oncology
سنة النشر: 2020
مصطلحات موضوعية: Original Article, info, edu
الوصف: BACKGROUND: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey for diverse queries faced in the treatment of brain tumors. As part I of the survey, the aim of this study is to evaluate national patterns of clinical practice about antiepileptic drug (AED) and steroid usage for management of brain tumors. METHODS: A web-based survey was sent to all members of the KSNO by email. The survey included 9 questions of AED usage and 5 questions of steroid usage for brain tumor patients. All questions were developed by consensus of the Guideline Working Group. RESULTS: The overall response rate was 12.8% (54/423). Regarding AED usage, the majority of respondents (95.2%) routinely prescribed prophylactic AEDs for patients with seizure at the peri/postoperative period. However, as many as 72.8% of respondents prescribed AED routinely for seizure-naïve patients, and others prescribed AED as the case may be. The duration of AED prophylaxis showed wide variance according to the epilepsy status and the location of tumor. Levetiracetam (82.9%) was the most preferred AED for epilepsy prophylaxis. Regarding steroid usage, 90.5% of respondents use steroids in perioperative period, including 34.2% of them as a routine manner. Presence of peritumoral edema (90.9%) was considered as the most important factor determining steroid usage followed by degree of clinical symptoms (60.6%). More than half of respondents (51.2%) replied to discontinue the steroids within a week after surgery if there are no specific medical conditions, while 7.3% preferred slow tapering up to a month after surgery. CONCLUSION: The survey demonstrated the prevailing practice patterns on AED and steroid usage in neuro-oncologic field among members of the KSNO. This information provides a point of reference for establishing a practical guideline in the management of brain tumor patients.
نوع الوثيقة: text
اللغة: English
العلاقة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221462Test/
الإتاحة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221462Test/
حقوق: undefined
رقم الانضمام: edsbas.4A0305B0
قاعدة البيانات: BASE