دورية أكاديمية
Antimicrobial Efficacy of a Vegetable Oil Plasticizer in PVC Matrices
| العنوان: | Antimicrobial Efficacy of a Vegetable Oil Plasticizer in PVC Matrices |
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| المؤلفون: | Bajetto, Greta, Scutera, Sara, Menotti, Francesca, Banche, Giuliana, Chiaradia, Giuseppe, Turesso, Caterina, De Andrea, Marco, Vallino, Marta, van Es, Daan, Biolatti, Matteo, Dell’Oste, Valentina, Musso, Tiziana |
| المصدر: | Polymers 16 (2024) 8 ; ISSN: 2073-4360 |
| سنة النشر: | 2024 |
| المجموعة: | Wageningen UR (University & Research Centre): Digital Library |
| مصطلحات موضوعية: | antiviral and antibacterial polymers, biomaterials, medical devices, plasticizers, polyvinyl chloride (PVC), vegetable oils |
| الوصف: | The growing prevalence of bacterial and viral infections, highlighted by the recent COVID-19 pandemic, urgently calls for new antimicrobial strategies. To this end, we have synthesized and characterized a novel fatty acid epoxy-ester plasticizer for polymers, named GDE. GDE is not only sustainable and user-friendly but also demonstrates superior plasticizing properties, while its epoxy components improve the heat stability of PVC-based matrices. A key feature of GDE is its ability to confer antimicrobial properties to surfaces. Indeed, upon contact, this material can effectively kill enveloped viruses, such as herpes simplex virus type 1 (HSV-1) and the β-coronavirus prototype HCoV-OC43, but it is ineffective against nonenveloped viruses like human adenovirus (HAdV). Further analysis using transmission electron microscopy (TEM) on HSV-1 virions exposed to GDE showed significant structural damage, indicating that GDE can interfere with the viral envelope, potentially causing leakage. Moreover, GDE demonstrates antibacterial activity, albeit to a lesser extent, against notorious pathogens such as Staphylococcus aureus and Escherichia coli. Overall, this newly developed plasticizer shows significant potential as an antimicrobial agent suitable for use in both community and healthcare settings to curb the spread of infections caused by microorganisms contaminating physical surfaces. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://edepot.wur.nl/658129Test; https://research.wur.nl/en/publications/antimicrobial-efficacy-of-a-vegetable-oil-plasticizer-in-pvc-matrTest |
| DOI: | 10.3390/polym16081046 |
| الإتاحة: | https://doi.org/10.3390/polym16081046Test https://research.wur.nl/en/publications/antimicrobial-efficacy-of-a-vegetable-oil-plasticizer-in-pvc-matrTest |
| حقوق: | https://creativecommons.org/licenses/by/4.0Test/ ; Wageningen University & Research |
| رقم الانضمام: | edsbas.48B78557 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/polym16081046 |
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