دورية أكاديمية
Trends in the characteristics and perioperative outcomes of patients undergoing laparoscopic and open resections for benign liver lesions: an international multicenter retrospective cohort study of 845 patients
| العنوان: | Trends in the characteristics and perioperative outcomes of patients undergoing laparoscopic and open resections for benign liver lesions: an international multicenter retrospective cohort study of 845 patients |
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| المؤلفون: | Sijberden, Jasper P., Zimmitti, Giuseppe, Cipriani, Federica, Furumaya, Alicia, Lanari, Jacopo, Suhool, Amal, Osei-Bordom, Daniel, Aghayan, Davit, Jovine, Elio, Ruzzenente, Andrea, Ardito, Francesco, D'Hondt, Mathieu, Ferrero, Alessandro, Benedetti Cacciaguerra, Andrea, Lopez-Ben, Santi, Dagher, Ibrahim, Fuks, David, Alseidi, Adnan, Rotellar, Fernando, di Benedetto, Fabrizio, Ratti, Francesca, Swijnenburg, Rutger-Jan, Gringeri, Enrico, Vivarelli, Marco, Giuliante, Felice, Edwin, Bjørn, Sutcliffe, Robert P., Primrose, John N., Cillo, Umberto, Besselink, Marc G., Aldrighetti, Luca A., Abu Hilal, Mohammad |
| سنة النشر: | 2024 |
| المجموعة: | University of Southampton: e-Prints Soton |
| الوصف: | Background: Solid benign liver lesions (BLL) are increasingly discovered, but clear indications for surgical treatment are often lacking. Concomitantly, laparoscopic liver surgery is increasingly performed. The aim of this study was to assess if the availability of laparoscopic surgery has had an impact on the characteristics and perioperative outcomes of patients with BLL. Methods: This is a retrospective international multicenter cohort study, including patients undergoing a laparoscopic or open liver resection for BLL from 19 centers in eight countries. Patients were divided according to the time period in which they underwent surgery (2008–2013, 2014–2016, and 2017–2019). Unadjusted and risk-adjusted (using logistic regression) time-trend analyses were performed. The primary outcome was textbook outcome (TOLS), defined as the absence of intraoperative incidents ≥ grade 2, bile leak ≥ grade B, severe complications, readmission and 90-day or in-hospital mortality, with the absence of a prolonged length of stay added to define TOLS+. Results: In the complete dataset comprised of patients that underwent liver surgery for all indications, the proportion of patients undergoing liver surgery for benign disease remained stable (12.6% in the first time period, 11.9% in the second time period and 12.1% in the last time period, p = 0.454). Overall, 845 patients undergoing a liver resection for BLL in the first (n = 374), second (n = 258) or third time period (n = 213) were included. The rates of ASA-scores≥3 (9.9%–16%,p < 0.001), laparoscopic surgery (57.8%–77%,p < 0.001), and Pringle maneuver use (33.2%–47.2%,p = 0.001) increased, whereas the length of stay decreased (5 to 4 days,p < 0.001). There were no significant changes in the TOLS rate (86.6%–81.3%,p = 0.151), while the TOLS + rate increased from 41.7% to 58.7% (p < 0.001). The latter result was confirmed in the risk-adjusted analyses (aOR 1.849,p = 0.004). Conclusion: The surgical treatment of BLL has evolved with an increased implementation of the ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://eprints.soton.ac.uk/485114/1/1-s2.0-S1365182X23019718-main.pdfTest; https://eprints.soton.ac.uk/485114/2/PIIS1365182X23019718.pdfTest; Sijberden, Jasper P., Zimmitti, Giuseppe and Cipriani, Federica , et al. (2024) Trends in the characteristics and perioperative outcomes of patients undergoing laparoscopic and open resections for benign liver lesions: an international multicenter retrospective cohort study of 845 patients. HPB, 26 (2), 188-202. (doi:10.1016/j.hpb.2023.10.016 ). |
| الإتاحة: | https://doi.org/10.1016/j.hpb.2023.10.016Test https://eprints.soton.ac.uk/485114Test/ https://eprints.soton.ac.uk/485114/1/1-s2.0-S1365182X23019718-main.pdfTest https://eprints.soton.ac.uk/485114/2/PIIS1365182X23019718.pdfTest |
| حقوق: | cc_by_4 |
| رقم الانضمام: | edsbas.48B4F3C0 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |