دورية أكاديمية
Can Desensitizing Toothpastes Also Have an Effect on Gingival Inflammation? A Double-Blind, Three-Treatment Crossover Clinical Trial
| العنوان: | Can Desensitizing Toothpastes Also Have an Effect on Gingival Inflammation? A Double-Blind, Three-Treatment Crossover Clinical Trial |
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| المؤلفون: | Monterubbianesi, Riccardo, Sparabombe, Scilla, Tosco, Vincenzo, Profili, Fabia, Mascitti, Marco, Hosein, Andrell, Putignano, Angelo, Orsini, Giovanna |
| المساهمون: | Monterubbianesi, Riccardo, Sparabombe, Scilla, Tosco, Vincenzo, Profili, Fabia, Mascitti, Marco, Hosein, Andrell, Putignano, Angelo, Orsini, Giovanna |
| سنة النشر: | 2020 |
| المجموعة: | Università Politecnica delle Marche: IRIS |
| الوصف: | Background: Many desensitizing toothpastes exist commercially; however, few clinical trials have investigated their anti-inflammatory effects. This study aimed to evaluate the anti-inflammatory effect and patient appreciation of two toothpastes containing desensitizing agents: (1) a zinc-carbonate-hydroxyapatite nanoparticle (CHA) and (2) a calcium sodium phosphosilicate bioactive glass (CSPS). Methods: CHA and CSPS were compared with an anti-inflammatory and antibacterial herbal based toothpaste (HB). The aims were accomplished by comparing the following outcomes: (1) the reduction in plaque and bleeding score (Full Mouth Plaque Score (FMPS) and Full Mouth Bleeding Score (FMBS), respectively); (2) the antibacterial activity (AbA) of the toothpaste by saliva samples; (3) the patient appreciation score (Visual Analogue Scale; VAS). Clinical parameters were assessed at baseline and 14 days post-treatment. Results: The final sample consisted of 25 subjects, aged between 20 and 58 years. Although no differences in FMPS were reported (p > 0.05), both desensitizing toothpastes showed an improvement in FMBS. CSPS and HB recorded more AbA compared to CHA (p < 0.05). Moreover, HB resulted in a higher VAS score than both desensitizing toothpastes (p < 0.05). Conclusion: In conclusion, only CSPS displayed a similar anti-inflammatory effect compared to HB. Despite the low VAS score, CSPS could be considered as a valid and effective toothpaste in subjects with both dentin hypersensitivity and inflamed gums, highlighting its utility in clinical practice. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000597590200001; volume:17; issue:23; firstpage:8927; journal:INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH; http://hdl.handle.net/11566/285651Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85096990777 |
| DOI: | 10.3390/ijerph17238927 |
| الإتاحة: | https://doi.org/10.3390/ijerph17238927Test http://hdl.handle.net/11566/285651Test |
| رقم الانضمام: | edsbas.4838AA4C |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/ijerph17238927 |
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