دورية أكاديمية

Impact of carcinomatosis and ascites status on long-term outcomes of palliative treatment for patients with gastric outlet obstruction caused by unresectable gastric cancer: stent placement versus palliative gastrojejunostomy

التفاصيل البيبلوغرافية
العنوان: Impact of carcinomatosis and ascites status on long-term outcomes of palliative treatment for patients with gastric outlet obstruction caused by unresectable gastric cancer: stent placement versus palliative gastrojejunostomy
المساهمون: Chan Hyuk Park, Jun Chul Park, Eun Hye Kim, Hyunsoo Chung, Ji Yeong An, Hyoung-Il Kim, Sung Kwan Shin, Sang Kil Lee, Jae-Ho Cheong, Woo Jin Hyung, Yong Chan Lee, Sung Hoon Noh, Choong Bae Kim, Kim, Eun Hye, Kim, Choong Bai, Kim, Hyoung Il, Noh, Sung Hoon, Park, Jun Chul, Park, Chan Hyuk, Shin, Sung Kwan, An, Ji Yeong, Lee, Sang Kil, Lee, Yong Chan, Cheong, Jae Ho, Chung, Hyun Soo, Hyung, Woo Jin
سنة النشر: 2015
مصطلحات موضوعية: Aged, Ascites/etiology, Ascites/pathology, Ascites/therapy, Carcinoma/complications, Carcinoma/pathology, Carcinoma/therapy, Female, Gastric Bypass, Gastric Outlet Obstruction/etiology, Gastric Outlet Obstruction/pathology, Gastric Outlet Obstruction/therapy, Humans, Male, Middle Aged, Palliative Care, Retrospective Studies, Stents, Stomach Neoplasms/complications, Stomach Neoplasms/pathology, Stomach Neoplasms/therapy, Treatment Outcome
الوصف: BACKGROUND: Self-expandable metal stent (SEMS) placement and palliative gastrojejunostomy (GJJ) are palliative treatment options for malignant gastric outlet obstruction. OBJECTIVE: To compare clinical outcomes of palliative treatments for gastric outlet obstruction caused by unresectable gastric cancer. DESIGN: Retrospective study. SETTING: University-affiliated tertiary-care hospital in the Republic of Korea. PATIENTS: Two hundred fifty-six patients with gastric outlet obstruction caused by unresectable gastric cancer. INTERVENTION: SEMS placement and palliative GJJ. MAIN OUTCOME MEASUREMENTS: Patency duration and overall survival duration. RESULTS: In total, 217 and 39 patients underwent SEMS placement and palliative GJJ, respectively, as an initial palliative treatment. Treatment modality affected reobstruction after clinical success (hazard ratio [HR] [95% confidence interval {CI}], 0.5 [0.3-0.8] of palliative GJJ). In addition, carcinomatosis with ascites was an independent associated factor of clinical success and reobstruction (HR [95% CI], 0.3 [0.1-0.7] and 1.4 [1.0-2.0], respectively). In a subgroup of patients with good performance who had neither carcinomatosis nor ascites, patency duration and overall survival duration did not differ between the 2 groups (P = .079 and P = .290, respectively). In patients with good performance who had carcinomatosis without ascites, patency duration was longer in the palliative GJJ group than in the SEMS placement group (P = .016). Overall survival, however, did not differ between the 2 groups (P = .062). In a subgroup of patients with good performance who had carcinomatosis with ascites, both patency duration and overall survival were longer in the palliative GJJ group than in the SEMS placement group (P = .007 and P = .012, respectively). LIMITATIONS: Nonrandomized, retrospective study. CONCLUSION: Long-term clinical outcomes of the palliative treatment modality for gastric outlet obstruction caused by unresectable gastric cancer were affected by carcinomatosis and ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: 321~332
اللغة: unknown
تدمد: 0016-5107
1097-6779
العلاقة: GASTROINTESTINAL ENDOSCOPY; J00920; OAK-2015-00553; https://ir.ymlib.yonsei.ac.kr/handle/22282913/139713Test; http://www.sciencedirect.com/science/article/pii/S0016510714018598Test; T201500819; GASTROINTESTINAL ENDOSCOPY, Vol.81(2) : 321-332, 2015
DOI: 10.1016/j.gie.2014.06.024
الإتاحة: https://doi.org/10.1016/j.gie.2014.06.024Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139713Test
http://www.sciencedirect.com/science/article/pii/S0016510714018598Test
حقوق: CC BY-NC-ND 2.0 KR ; https://creativecommons.org/licenses/by-nc-nd/2.0/krTest/ ; not free
رقم الانضمام: edsbas.47606E0C
قاعدة البيانات: BASE
الوصف
تدمد:00165107
10976779
DOI:10.1016/j.gie.2014.06.024