The MPS II; comparison with the Macular Pigment Reflectometer and the Macular Densitometer

التفاصيل البيبلوغرافية
العنوان: The MPS II; comparison with the Macular Pigment Reflectometer and the Macular Densitometer
المؤلفون: Patryas, L, Cher, J, Leung, IYF, Neelam, K, Makridaki, M, Carden, D, Berendschot, TTJM, Veen, RLP van der, Murray, IJ
المصدر: Patryas , L , Cher , J , Leung , IYF , Neelam , K , Makridaki , M , Carden , D , Berendschot , TTJM , Veen , RLP V D & Murray , IJ 2013 , ' The MPS II; comparison with the Macular Pigment Reflectometer and the Macular Densitometer ' , Macular Carotenoid Conference , Cambridge , 1/01/24 .
سنة النشر: 2013
المجموعة: The University of Manchester: Research Explorer - Publications
الوصف: Purpose: Measuring macular pigment optical density (MPOD) with different methods appear to produce differing results in the same individuals, especially when dissimilar principles are employed. Ascertaining to what degree these methods correlate will enable the scientific community to interpret past and future research studies in this field. Here we describe two series of experiments which compare recent techniques used to measure MPOD. Methods: First, we used a macular pigment reflectometer1 (MPR) with capture angle 1, modified to measure at eccentricities of 0, 1, 2, 4, 6 and 8. These data were compared with those obtained from the Macular Pigment Screener2 (MPS) modified to assess MPOD at 0.5, 1, 2, 4, 5, 6 and 7. Nineteen healthy individuals (mean age 26 8 years) were tested. In a second experiment, we compared the right eyes of twenty-five healthy individuals (mean age 23 3 years) using MPS and a Macular Densitometer2 (MD).Results: There was a strong correlation between the MPR and the MPR techniques (r = 0.72, p = 0.001) with the absolute estimates obtained by MPS being lower than by MPR. These differences could be explained by i) non-zero values at 8 eccentricity and ii) assuming the subjects used a point 0.4 from the centre of the stimulus to set flicker thresholds. The correlation between the MPS and MD was high (r = 0.82, p <0.0001), with the MPS again producing lower absolute values. Repeatability was assessed with 10 individuals. Coefficients of repeatability for MPD and MPS were 0.21 and 0.06, respectively. Conclusions: The MPS, the MPR and the MD provide broadly similar results. It is inevitable that different absolute values are obtained, The important factor is the predictability from one method to another. It is essential that practitioners obtain normative data for any particular instrument as it is well known that many factors influence the assessment of MPOD. The MPS has the advantage of the centre-only facility, designed for clinical practice. This enables rapid ...
نوع الوثيقة: conference object
اللغة: English
الإتاحة: https://research.manchester.ac.uk/en/publications/6d536c7b-9992-4e67-b3fd-a08d14e307eaTest
حقوق: info:eu-repo/semantics/restrictedAccess
رقم الانضمام: edsbas.45FC5EEC
قاعدة البيانات: BASE