دورية أكاديمية
Metabolic syndrome in young Czech women with polycystic ovary syndrome
| العنوان: | Metabolic syndrome in young Czech women with polycystic ovary syndrome |
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| المؤلفون: | Vrbíková, J., Vondra, K., Cibula, D., Dvoráková, K., Stanická, S., Srámková, D., Sindelka, G., Hill, M., Bendlová, B., Skrha, J. |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2005 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | Reproductive Endocrinology |
| الوصف: | METHODS: Sixty-nine young women with polycystic ovary syndrome (PCOS) [age 25.2 6 4.7 years, with body mass index (BMI) 24.3 6 4.8 kg/m2; mean 6 SD] and 73 age-matched healthy females (BMI 22.3 6 3.3 kg/m2; mean 6 SD) were evaluated for the occurrence of features of metabolic syndrome according to the Adult Treatment Panel III. RESULTS: Overt metabolic syndrome (the presence of three and more risk factors) was not more common in PCOS women (1/64, 1.6%) than in healthy controls (0/73, 0%). On the other hand, in nearly 50% of PCOS women isolated features of metabolic syndrome, most often a decrease in high-density lipoprotein (HDL) cholesterol, were found. Women with at least one feature of metabolic syndrome were, in comparison with women without any of these features, significantly more obese ( P = 0.0001), with lower insulin sensitivity ( P = 0.05). When comparing PCOS women according to the degree of insulin sensitivity, as determined by euglycaemic clamp, isolated features of metabolic syndrome were found in 8/17 women above the upper quartile, compared with 11/16 women below the lower quartile of insulin sensitivity ( P = 0.20). CONCLUSIONS: Overt metabolic syndrome is only rarely encountered in young Czech females affected by PCOS but its isolated features are relatively frequent, both in young PCOS patients and in age-matched control women. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | http://humrep.oxfordjournals.org/cgi/content/short/20/12/3328Test; http://dx.doi.org/10.1093/humrep/dei221Test |
| DOI: | 10.1093/humrep/dei221 |
| الإتاحة: | https://doi.org/10.1093/humrep/dei221Test http://humrep.oxfordjournals.org/cgi/content/short/20/12/3328Test |
| حقوق: | Copyright (C) 2005, European Society of Human Reproduction and Embryology |
| رقم الانضمام: | edsbas.44FAA69A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/humrep/dei221 |
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