دورية أكاديمية
Impact of body mass index on prevalence of multimorbidity in primary care: Cohort study
| العنوان: | Impact of body mass index on prevalence of multimorbidity in primary care: Cohort study |
|---|---|
| المؤلفون: | Booth, HP, Prevost, AT, Gulliford, MC |
| المصدر: | 43 ; 38 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2013 |
| المجموعة: | Imperial College London: Spiral |
| مصطلحات موضوعية: | Science & Technology, Life Sciences & Biomedicine, Primary Health Care, Medicine, General & Internal, General & Internal Medicine, Cardiovascular diseases, comorbidity, diabetes mellitus, family practice, obesity, LIFE-STYLE INTERVENTION, SMOKING-CESSATION, EPIDEMIOLOGY, OVERWEIGHT, BURDEN, WEIGHT, Adult, Aged, 80 and over, Body Mass Index, Chronic Disease, Cohort Studies, Female, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Odds Ratio |
| الوصف: | Background. Multimorbidity is the co-occurrence of long-term conditions. Obesity is associated with an increased risk of long-term conditions including type 2 diabetes and depression. Objective. To quantify the association between body mass index (BMI) category and multimorbidity in a large cohort registered in primary care. Methods. The sample comprised primary care electronic health records of adults aged ≥30 years, sampled from the Clinical Practice Research Datalink between 2005 and 2011. Multimorbidity was defined as the co-occurrence of ≥2 of 11 conditions affecting seven organ systems. Age- and sex-standardized prevalence of multimorbidity was estimated by BMI category. Adjusted odds ratios associating BMI with additional morbidity were estimated adjusting for socioeconomic deprivation and smoking. Results. The sample comprised 300 006 adults. After excluding participants with BMI never recorded, data were analysed for 223 089 (74%) contributing 1 374 109 person–years. In normal weight men, the standardized prevalence of multimorbidity was 23%, rising to 27% in overweight, 33% in category I obesity, 38% in category II and 44% in category III obesity. In women, the corresponding values were 28%, 34%, 41%, 45% and 51%. In category III obesity, the adjusted odds, relative to normal BMI, were 2.24 (2.13–2.36) for a first condition; 2.63 (2.51–2.76) for a second condition and 3.09 (2.92–3.28) for three or more conditions. In a cross-sectional analysis, 32% of multimorbidity was attributable to overweight and obesity. Conclusions. Multiple morbidity is highly associated with increasing BMI category and obesity, highlighting the potential for targeted primary and secondary prevention interventions in primary care. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0263-2136 |
| العلاقة: | Family Practice; http://hdl.handle.net/10044/1/72021Test; https://dx.doi.org/10.1093/fampra/cmt061Test |
| DOI: | 10.1093/fampra/cmt061 |
| الإتاحة: | https://doi.org/10.1093/fampra/cmt061Test http://hdl.handle.net/10044/1/72021Test |
| حقوق: | © 2013 The Author. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0Test/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| رقم الانضمام: | edsbas.448800F9 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 02632136 |
|---|---|
| DOI: | 10.1093/fampra/cmt061 |