دورية أكاديمية

Single-cell transcriptomic landscape and the microenvironment of normal adjacent tissues in hypopharyngeal carcinoma ...

التفاصيل البيبلوغرافية
العنوان: Single-cell transcriptomic landscape and the microenvironment of normal adjacent tissues in hypopharyngeal carcinoma ...
المؤلفون: Guan, Rui, Li, Ce, Gu, Fangmeng, Li, Wenming, Wei, Dongmin, Cao, Shengda, Chang, Fen, Lei, Dapeng
بيانات النشر: figshare
سنة النشر: 2024
المجموعة: DataCite Metadata Store (German National Library of Science and Technology)
مصطلحات موضوعية: Biophysics, Physical Sciences not elsewhere classified, Cell Biology, Molecular Biology, Physiology, FOS Biological sciences, Biotechnology, Chemical Sciences not elsewhere classified, Immunology, FOS Clinical medicine, Biological Sciences not elsewhere classified, Cancer, Hematology
الوصف: Background The cellular origin of hypopharyngeal diseases is crucial for further diagnosis and treatment, and the microenvironment in tissues may also be associated with specific cell types at the same time. Normal adjacent tissues (NATs) of hypopharyngeal carcinoma differ from non-tumor-bearing tissues, and can influenced by the tumor. However, the heterogeneity in kinds of disease samples remains little known, and the transcriptomic profile about biological information associated with disease occurrence and clinical outcome contained in it has yet to be fully evaluated. For these reasons, we should quickly investigate the taxonomic and transcriptomic information of NATs in human hypopharynx. Results Single-cell suspensions of normal adjacent tissues (NATs) of hypopharyngeal carcinoma were obtained and single-cell RNA sequencing (scRNA-seq) was performed. We present scRNA-seq data from 39,315 high-quality cells in the hypopharyngeal from five human donors, nine clusters of normal adjacent human ...
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
DOI: 10.6084/m9.figshare.c.7240996
الإتاحة: https://doi.org/10.6084/m9.figshare.c.7240996Test
https://springernature.figshare.com/collections/Single-cell_transcriptomic_landscape_and_the_microenvironment_of_normal_adjacent_tissues_in_hypopharyngeal_carcinoma/7240996Test
حقوق: Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcodeTest ; cc-by-4.0
رقم الانضمام: edsbas.4290993F
قاعدة البيانات: BASE