دورية أكاديمية
Distribution of P2X receptor subtypes in the rat female reproductive tract at late pro-oestrus/early oestrus.
| العنوان: | Distribution of P2X receptor subtypes in the rat female reproductive tract at late pro-oestrus/early oestrus. |
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| المساهمون: | Michelle Bardini, Hye Yeon Lee, Geoffrey Burnstock, Lee, Hye Yeon |
| بيانات النشر: | Institute Of Physics And The Physical Society |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | Amino Acid Sequence, Animals, Antibodies, Cervix Uteri/cytology, Cervix Uteri/physiology, Endometrium/cytology, Endometrium/physiology, Estrus/physiology, Female, Genitalia, Male/physiology, Immunohistochemistry, Male, Molecular Sequence Data, Muscle, Smooth/cytology, Smooth/physiology, Ovary/cytology, Ovary/physiology, Peptide Fragments/chemistry, Peptide Fragments/immunology, Rats, Sprague-Dawley, Receptors, Purinergic P2/analysis, Purinergic P2/chemistry, Purinergic P2/metabolism, Uterus/cytology, Uterus/physiology, Vagina/cytology |
| الوصف: | Using immunohistochemistry techniques, we have examined the female reproductive organs of the rat in late pro-oestrus/early oestrus for the presence of purine nucleotide P2X1-7 receptors. In contrast to the male genital organs and the urinary tract, P2X1 receptors were present weakly, if at all, on smooth muscle membranes, except in blood vessels, whereas P2X2 immunoreactivity in smooth muscle was present in ovary and uterus as well as in blood vessels. Neither P2X1 nor P2X2 receptors were present in fallopian tubes. P2X5 receptors were seen in the differentiating cell layers of the stratified squamous vaginal epithelium and also in the very early stages of ovarian follicular development; P2X6 receptors were present in secondary follicles. P2X7 receptors, markers for programmed cell death, were present in the keratinised vaginal epithelium and also in the exfoliating superficial endometrial cells. The possible biological significance of these signalling molecules in the female reproductive tract is discussed. ; restriction |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0022-3727 |
| العلاقة: | Journal of Physics D - Applied Physics; J01708; OAK-2000-00375; https://ir.ymlib.yonsei.ac.kr/handle/22282913/171737Test; https://link.springer.com/article/10.1007/s004419900138Test; T200002814; Journal of Physics D - Applied Physics, Vol.299(1) : 105-113, 2000 |
| DOI: | 10.1007/s004419900138 |
| الإتاحة: | https://doi.org/10.1007/s004419900138Test https://ir.ymlib.yonsei.ac.kr/handle/22282913/171737Test |
| حقوق: | CC BY-NC-ND 2.0 KR |
| رقم الانضمام: | edsbas.420F46B8 |
| قاعدة البيانات: | BASE |
| تدمد: | 00223727 |
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| DOI: | 10.1007/s004419900138 |