التفاصيل البيبلوغرافية
| العنوان: |
Cognitive competence at the onset of West syndrome: correlation with EEG patterns and visual function |
| المؤلفون: |
Randò, Teresa, Baranello, Giovanni, Ricci, Daniela, Guzzetta, Andrea, Tinelli, Francesca, Biagioni, Enrico, La Torre, Giuseppe, Epifanio, Roberta, Signorini, Sabrina, Fazzi, Elisa, Mercuri, Eugenio, Cioni, Giovanni, Guzzetta, Francesco |
| المصدر: |
Developmental Medicine & Child Neurology ; volume 47, issue 11, page 760-765 ; ISSN 0012-1622 1469-8749 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2005 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
The aim of this study was to evaluate cognitive development at the onset of West syndrome (WS) with regard to electroencephalogram (EEG) patterns and visual function. Twenty‐five patients (14 males, 11 females) at the onset of spasms ( T 0 ) in WS and 2 months later ( T 1 ) underwent a full clinical evaluation, including neuroimaging, cognitive assessment, video‐EEG, and visual function. Mean age of the patients at spasm onset was 5.9 months (SD 2.5; range 2 to 13mo). Cognitive development, assessed with Griffiths Mental Development Scales (GMDS), was generally impaired at T 0 and was significantly related to visual function ( p <0.001) at both T 0 and T 1 In general, there was a specific major impairment in the eye–hand coordination scale of the GMDS which tended to disappear after 2 months in less severe cases. At the onset of spasms, sleep EEG organization seemed to be better related to cognitive abilities than awake hypsarrhythmia. These results support a close link between visual function and cognitive competence in WS and provide additional information to improve the understanding of possible mechanisms underlying cognitive impairment. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/j.1469-8749.2005.tb01074.x |
| الإتاحة: |
https://doi.org/10.1111/j.1469-8749.2005.tb01074.xTest |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.412B16B7 |
| قاعدة البيانات: |
BASE |
