S1 File -

التفاصيل البيبلوغرافية
العنوان: S1 File -
المؤلفون: Min Ye, Ai Hong Yuan, Qi Qi Yang, Qun Wei Li, Fei Yue Li, Yan Wei
سنة النشر: 2024
مصطلحات موضوعية: Medicine, Genetics, Biotechnology, Developmental Biology, Science Policy, Hematology, Infectious Diseases, Virology, still controversy regarding, joanna briggs institute, glycemic management among, china national knowledge, present research intends, technology periodical database, observational studies investigating, critical appraisal method, response curve analysis, analysis , knowledge gaps, preclinical research, little research, %22">xlink ">, vip ), two researchers, third researcher, t2dm ), stata software, significant effects, robis tool, ottawa scale
الوصف: Introduction With an incidence rate as high as 46%-58%, hypoglycemia is a common complication of glycemic management among those suffering from type 2 diabetes mellitus(T2DM). According to preclinical research, hypoglycemia episodes may impair cognition by harming neurons. However, there is still controversy regarding the clinical evidence for the relationship between hypoglycemic events and the likelihood of cognitive impairment. Furthermore, little research has been done on the dose-response association between hypoglycemia incidents and the possibility of cognitive impairment. To address these knowledge gaps, the present research intends to update the comprehension of the association among hypoglycemic events and the risk of cognitive impairment and to clarify the correlation between dose and response by incorporating the most recent investigations. Method and analysis This work has developed a protocol for a systematic review and meta-analysis that will examine, via a well-organized assessment of several databases, the relationship between the incidence of hypoglycemia and the probability of cognitive impairment. Observational studies investigating the connection between hypoglycemia episodes and cognitive impairment will be included. The databases that will be searched are PubMed, Web of Science, the Chinese Biomedical Literature Database (CBM), Cochrane Library, Embase, the China National Knowledge (CNKI), Wan Fang, the Chinese Science and Technology Periodical Database (VIP), and Du Xiu. Literature from the establishment of each database to December 2023 will be included in the search. Two researchers will independently screen the studies that satisfy the requirements for both inclusion and exclusion. A third researcher will be asked to mediate any disputes. The methodological caliber of the studies included will be assessed utilizing the Newcastle-Ottawa Scale (NOS) or the Joanna Briggs Institute (JBI) critical appraisal method. With regard to GRADE, which stands for Grading of Recommendations, ...
نوع الوثيقة: dataset
اللغة: unknown
العلاقة: https://figshare.com/articles/dataset/S1_File_-/25135638Test
DOI: 10.1371/journal.pone.0296662.s004
الإتاحة: https://doi.org/10.1371/journal.pone.0296662.s004Test
https://figshare.com/articles/dataset/S1_File_-/25135638Test
حقوق: CC BY 4.0
رقم الانضمام: edsbas.40A47044
قاعدة البيانات: BASE