التفاصيل البيبلوغرافية
| العنوان: |
Feature similarity gradients detect alterations in the neonatal cortex associated with preterm birth |
| المؤلفون: |
Galdi, Paola, Cabez, Manuel Blesa, Farrugia, Christine, Vaher, Kadi, Williams, Logan Z. J., Sullivan, Gemma, Stoye, David Q., Quigley, Alan J., Makropoulos, Antonios, Thrippleton, Michael J., Bastin, Mark E., Richardson, Hilary, Whalley, Heather, Edwards, A. David, Bajada, Claude J., Robinson, Emma C., Boardman, James P. |
| المساهمون: |
UK Research and Innovation, Wellcome Trust, Commonwealth Scholarship Commission |
| المصدر: |
Human Brain Mapping ; volume 45, issue 4 ; ISSN 1065-9471 1097-0193 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2024 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
The early life environment programmes cortical architecture and cognition across the life course. A measure of cortical organisation that integrates information from multimodal MRI and is unbound by arbitrary parcellations has proven elusive, which hampers efforts to uncover the perinatal origins of cortical health. Here, we use the Vogt‐Bailey index to provide a fine‐grained description of regional homogeneities and sharp variations in cortical microstructure based on feature gradients, and we investigate the impact of being born preterm on cortical development at term‐equivalent age. Compared with term‐born controls, preterm infants have a homogeneous microstructure in temporal and occipital lobes, and the medial parietal, cingulate, and frontal cortices, compared with term infants. These observations replicated across two independent datasets and were robust to differences that remain in the data after matching samples and alignment of processing and quality control strategies. We conclude that cortical microstructural architecture is altered in preterm infants in a spatially distributed rather than localised fashion. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1002/hbm.26660 |
| الإتاحة: |
https://doi.org/10.1002/hbm.26660Test |
| حقوق: |
http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.407714FC |
| قاعدة البيانات: |
BASE |
