دورية أكاديمية
Prevalence of Osteoporosis Assessed by DXA and/or CT in Severe Obese Patients
| العنوان: | Prevalence of Osteoporosis Assessed by DXA and/or CT in Severe Obese Patients |
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| المؤلفون: | Marion Halin, Edem Allado, Eliane Albuisson, Laurent Brunaud, Isabelle Chary-Valckenaere, Damien Loeuille, Didier Quilliot, Marine Fauny |
| المصدر: | Journal of Clinical Medicine, Vol 11, Iss 6114, p 6114 (2022) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | obesity, bone mineral density (BMD), scanographic bone attenuation coefficient (SBAC-L1), tomodensitometry/CT, dual-energy X-ray absorptiometry (DXA), Medicine |
| الوصف: | The primary objective was to evaluate bone fragility prevalence on dual X-ray absorptiometry (DXA) and computed tomography (CT) in patients with severe obesity. The secondary objective was to evaluate the risk factors for bone fragility. This monocentric study was conducted in patients with grade 2 and 3 obesity. Bone mineral density (BMD) and T-score were studied on DXA, and the scanographic bone attenuation coefficient of L1 (SBAC-L1) was measured on CT. Among the 1386 patients included, 1013 had undergone both DXA and CT within less than 2 years. The mean age was 48.4 (±11.4) years, 77.6% were women, and the mean BMI was 45.6 (±6.7) kg/m². Eight patients (0.8%) had osteoporosis in at least one site. The mean SBAC-L1 was 192.3 (±52.4) HU; 163 patients (16.1%) were under the threshold of 145 HU. Older age (OR[CI95] = 1.1 [1.08–1.16]), lower BMD on the femoral neck and spine (OR[CI95] = 0.04[0.005–0.33] and OR[CI95] = 0.001[0.0001–0.008], respectively), and higher lean mass (OR[CI95] = 1.1 [1.03–1.13]) were significantly associated with an SBAC-L1 ≤ 145 HU in multivariate analysis. Approximately 16% of patients with severe obesity were under the SBAC-L1 threshold, while less than 1% were classified as osteoporotic on DXA. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2077-0383 |
| العلاقة: | https://www.mdpi.com/2077-0383/11/20/6114Test; https://doaj.org/toc/2077-0383Test; https://doaj.org/article/fff56511691e431084e3b6f7ed546abcTest |
| DOI: | 10.3390/jcm11206114 |
| الإتاحة: | https://doi.org/10.3390/jcm11206114Test https://doaj.org/article/fff56511691e431084e3b6f7ed546abcTest |
| رقم الانضمام: | edsbas.3FDDD9C |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20770383 |
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| DOI: | 10.3390/jcm11206114 |