التفاصيل البيبلوغرافية
| العنوان: |
Effect of treatment with an overheated dry-saturated steam vapour disinfection system on multidrug and extensively drug-resistant nosocomial pathogens and comparison with sodium hypochlorite activity |
| المؤلفون: |
Bagattini, Maria, Buonocore, Raffaella, Giannouli, Maria, Mattiacci, Dario, Bellopede, Rossella, Grimaldi, Nicola, Nardone, Antonio, Zarrilli, Raffaele, Triassi, Maria |
| بيانات النشر: |
BioMed Central Ltd. |
| سنة النشر: |
2015 |
| المجموعة: |
BioMed Central |
| مصطلحات موضوعية: |
Steam vapour disinfection system, Chlorine or hypochlorite disinfection, Nosocomial pathogens, Multidrug and extensively drug-resistant bacteria |
| الوصف: |
Background The development of portable steam generators has made disinfection of the environment more practical. This study assessed the “in vitro” ability of an overheated dry-saturated steam vapour system to kill multidrug and extensively-drug resistant nosocomial pathogens, defining the antimicrobial spectrum and the contact times compared with the activity of sodium hypochlorite. Methods The antibacterial efficacy of the overheated dry-saturated steam vapour system and of sodium hypochlorite against nosocomial pathogen isolates: extensively drug-resistant Acinetobacter baumannii , Pseudomonas aeruginosa , carbapenemase-producing Klebsiella pneumoniae , methicillin-resistant Staphylococcus aureus , high-level aminoglycoside-resistant Enterococcus faecalis , Candida parapsilosis and Aspergillus fumigatus were assessed using a surface time-kill test carried out on glass surfaces, with or without bovine serum albumin (BSA). Results The bactericidal activity of the overheated dry-saturated steam vapour system was observed at 180 °C after 5 min contact with or without BSA, using an initial inoculum of 10 9 CFU/mL. To reduce C. parapsilosis and A. fumigatus counts (from 10 7 CFU/mL), a longer contact time was necessary (7 min). In vitro tests with sodium hypochlorite at 5 % in the absence of an organic substance also resulted in an overall reduction in bacterial counts (from 10 9 CFU/mL) after 5 min of treatment. For mycotic challenge (10 7 CFU/mL), a longer contact time was necessary (7 min). In the presence of an organic substance, after 5 min, the hypochlorite reduced the viable count from 10 9 to 10 5 CFU/mL for all bacterial strains except E. faecalis that showed a reduction of 2 log units (10 9 to 10 7 CFU/mL). For C. parapsilosis and A. fumigatus , a 2 log unit reduction was observed after 7 min. Conclusions Steam disinfection of . |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
http://www.biomedcentral.com/1756-0500/8/551Test |
| الإتاحة: |
http://www.biomedcentral.com/1756-0500/8/551Test |
| حقوق: |
Copyright 2015 Bagattini et al. |
| رقم الانضمام: |
edsbas.3D6193A5 |
| قاعدة البيانات: |
BASE |
