رسالة جامعية

Influência do polimorfismo no gene da cyp1a2 sobre os efeitos da suplementação com o óleo essencial de hortelã-pimenta (Mentha piperita L.) no desempenho físico de corredores recreacionais

التفاصيل البيبلوغرافية
العنوان: Influência do polimorfismo no gene da cyp1a2 sobre os efeitos da suplementação com o óleo essencial de hortelã-pimenta (Mentha piperita L.) no desempenho físico de corredores recreacionais
المؤلفون: Miranda Neto, Manoel
المساهمون: Silva, Alexandre Sérgio, http://lattes.cnpq.br/9808224589301694Test
بيانات النشر: Universidade Federal da Paraíba
Brasil
Ciências da Nutrição
Programa de Pós-Graduação em Ciências da Nutrição
UFPB
سنة النشر: 2024
المجموعة: Universidade Federal da Paraiba: Biblioteca Digital de Teses e Dissertações
مصطلحات موضوعية: Óleo essencial - Desempenho físico - Corredores, Óleo essencial - Hortelã-pimenta, Alimento ergogênico, Exercício aeróbio, Polimorfismo genético, Essential oil - Physical performance - Runners, Essential oil - Peppermint, Ergogenic food, Aerobic exercise, Genetic polymorphism, CNPQ::CIENCIAS DA SAUDE::NUTRICAO
الوصف: Several foods have been proposed to improve physical performance. Peppermint essential oil (PEO) is among these foods, but there is still no data in the literature on its use in athletes and long-term events, and the mechanisms involved are still not clear. Meanwhile, individual variability in the ergogenic response to time to exhaustion (TTE) has been observed, and a possible explanation may be the presence of genetic polymorphisms. The objective of this study was to investigate the influence of PEO supplementation on the TTE of runners and whether the polymorphism in the CYP1A2 gene influences the responses to this supplementation. Forty male recreational runners (36.5±2.0 years; 24.3±0.6 kg/m2; 52.4±1.2 ml.kg.min) performed two procedures in a cross over model, one of which was experimental (500ml of water added with 0.05ml of PEO) and another isovolumetric placebo added with 0.05ml of mint essence. Thirty minutes later, they ran until exhaustion on a treadmill at 70% of VO2max, maintaining the intake of 100 ml of the experimental drink or placebo every 10 minutes during the first 40 minutes of the run. Before and every 10 minutes during exercise, body temperature and heart rate were recorded. Measurements of thermal sensation, thermal comfort and subjective perception of exertion were taken every 10 minutes during the physical test. Urine collection was done before and after exercise to record urinary volume and density. The sweating rate was calculated. Blood samples were taken at rest, immediately after the end of exercise and 2 hours after exercise, to measure Malondialdehyde and Total Oxidizing Capacity. The oral mucosa was collected for genotyping of the CYP1A2 gene. The first 14 runners ran 109.9 ± 7.4 minutes after ingesting the PEO and 98.5 ± 6.7 minutes in the placebo procedure, which was equivalent to a significant improvement of 11.6 ± 5.5% (p =0.009) (original article 1). For the total sample of 40 runners (original article 2), athletes ran 104.0 ± 5.1 minutes after ingesting PEO and 95.5 ± 3.9 ...
نوع الوثيقة: thesis
اللغة: Portuguese
العلاقة: https://repositorio.ufpb.br/jspui/handle/123456789/30063Test
الإتاحة: https://repositorio.ufpb.br/jspui/handle/123456789/30063Test
حقوق: Acesso aberto ; Attribution-NoDerivs 3.0 Brazil ; http://creativecommons.org/licenses/by-nd/3.0/brTest/
رقم الانضمام: edsbas.3D43B1C0
قاعدة البيانات: BASE