دورية أكاديمية
Optical Coherence Tomography Findings in Patients With Coronary Stent Thrombosis: A Report of the PRESTIGE Consortium (Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort).
| العنوان: | Optical Coherence Tomography Findings in Patients With Coronary Stent Thrombosis: A Report of the PRESTIGE Consortium (Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort). |
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| المؤلفون: | Adriaenssens, T., Joner, M., Godschalk, T. C., Malik, N., Alfonso, F., Xhepa, E., De Cock, D., Komukai, K., Tada, T., Cuesta, J., Sirbu, V., Feldman, L. J., Neumann, F-J., Goodall, Alison H., Heestermans, T., Buysschaert, I., Hlinomaz, O., Belmans, A., Desmet, W., Ten Berg, J. M., Gershlick, A. H., Massberg, S., Kastrati, A., Guagliumi, G., Byrne, R. A., Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Investigators |
| بيانات النشر: | American Heart Association |
| سنة النشر: | 2018 |
| المجموعة: | University of Leicester: Leicester Research Archive (LRA) |
| مصطلحات موضوعية: | atherosclerosis, malapposition, stents, thrombosis, tomography, optical coherence, uncovered struts, Aged, Coronary Thrombosis, Drug-Eluting Stents, Europe, Female, Humans, Male, Percutaneous Coronary Intervention, Prospective Studies, Registries, Research Report |
| الوصف: | BACKGROUND: Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. METHODS: Consecutive patients presenting with ST were prospectively enrolled in a registry by using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed with frequency domain OCT. Clinical data were collected according to a standardized protocol. OCT acquisitions were analyzed at a core laboratory. Dominant and contributing findings were adjudicated by an imaging adjudication committee. RESULTS: Two hundred thirty-one patients presenting with ST underwent OCT imaging; 14 (6.1%) had image quality precluding further analysis. Of the remaining patients, 62 (28.6%) and 155 (71.4%) presented with early and late/very late ST, respectively. The underlying stent type was a new-generation drug-eluting stent in 50.3%. Mean reference vessel diameter was 2.9±0.6 mm and mean reference vessel area was 6.8±2.6 mm2. Stent underexpansion (stent expansion index <0.8) was observed in 44.4% of patients. The predicted average probability (95% confidence interval) that any frame had uncovered (or thrombus-covered) struts was 99.3% (96.1-99.9), 96.6% (92.4-98.5), 34.3% (15.0-60.7), and 9.6% (6.2-14.5) and malapposed struts was 21.8% (8.4-45.6), 8.5% (4.6-15.3), 6.7% (2.5-16.3), and 2.0% (1.2-3.3) for acute, subacute, late, and very late ST, respectively. The most common dominant finding adjudicated for acute ST was uncovered struts (66.7% of cases); for subacute ST, the most common dominant finding was uncovered struts (61.7%) and underexpansion (25.5%); for late ST, the most common dominant finding was uncovered struts (33.3%) and severe restenosis (19.1%); and for very late ST, the most common dominant finding was neoatherosclerosis (31.3%) and uncovered struts ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0009-7322 1524-4539 |
| العلاقة: | https://www.ncbi.nlm.nih.gov/pubmed/28720725Test; Circulation, 2017, 136 (11), pp. 1007-1021; http://circ.ahajournals.org/content/136/11/1007Test; http://hdl.handle.net/2381/41891Test; CIRCULATIONAHA.117.026788 |
| DOI: | 10.1161/CIRCULATIONAHA.117.026788 |
| الإتاحة: | https://doi.org/10.1161/CIRCULATIONAHA.117.026788Test http://circ.ahajournals.org/content/136/11/1007Test http://hdl.handle.net/2381/41891Test |
| حقوق: | Copyright © the authors, 2017. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0Test/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
| رقم الانضمام: | edsbas.3D11E6E |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 00097322 15244539 |
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| DOI: | 10.1161/CIRCULATIONAHA.117.026788 |