التفاصيل البيبلوغرافية
العنوان: |
Generation and Functional Analysis of Defective Viral Genomes during SARS-CoV-2 Infection |
المؤلفون: |
Zhou, Terry, Gilliam, Nora J., Li, Sizhen, Spandau, Simone, Osborn, Raven M., Connor, Sarah, Anderson, Christopher S., Mariani, Thomas J., Thakar, Juilee, Dewhurst, Stephen, Mathews, David H., Huang, Liang, Sun, Yan |
المساهمون: |
Frieman, Matthew B., Griffin, Diane E., University of Rochester Technology Development Fund, University of Rochester HSCCI, Burroughs Wellcome Fund, HHS | NIH | National Center for Advancing Translational Sciences, HHS | NIH | National Heart, Lung, and Blood Institute, HHS | NIH | National Institute of General Medical Sciences, UR | School of Medicine and Dentistry, University of Rochester |
المصدر: |
mBio ; volume 14, issue 3 ; ISSN 2150-7511 |
بيانات النشر: |
American Society for Microbiology |
سنة النشر: |
2023 |
الوصف: |
Defective viral genomes (DVGs) are generated ubiquitously in many RNA viruses, including SARS-CoV-2. Their interference activity to full-length viruses and IFN stimulation provide the potential for them to be used in novel antiviral therapies and vaccine development. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1128/mbio.00250-23 |
الإتاحة: |
https://doi.org/10.1128/mbio.00250-23Test |
حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ ; https://journals.asm.org/non-commercial-tdm-licenseTest |
رقم الانضمام: |
edsbas.3BCB638E |
قاعدة البيانات: |
BASE |