دورية أكاديمية
Causes and consequences of child growth faltering in low-resource settings
| العنوان: | Causes and consequences of child growth faltering in low-resource settings |
|---|---|
| المؤلفون: | Mertens, A, Benjamin-Chung, J, Colford, JM, Coyle, J, van der Laan, MJ, Hubbard, AE, Rosete, S, Malenica, I, Hejazi, N, Sofrygin, O, Cai, W, Li, H, Nguyen, A, Pokpongkiat, NN, Djajadi, S, Seth, A, Jung, E, Chung, EO, Jilek, W, Subramoney, V, Hafen, R, Häggström, J, Norman, T, Brown, KH, Christian, P, Arnold, BF, Abbeddou, S, Adair, LS, Ahmed, T, Ali, A, Ali, H, Ashorn, P, Bahl, R, Barreto, ML, Becquey, E, Begín, F, Bessong, PO, Bhan, MK, Bhandari, N, Bhargava, SK, Bhutta, ZA, Black, RE, Bodhidatta, L, Carba, D, Checkley, W, Crabtree, JE, Dewey, KG, Duggan, CP, Fall, CHD, Faruque, ASG, Fawzi, WW, da Silva Filho, JQ, Gilman, RH, Guerrant, RL, Haque, R, Hasan, SMT, Hess, SY, Houpt, ER, Humphrey, JH, Iqbal, NT, Jimenez, EY, John, J, John, SM, Kang, G, Kosek, M, Kramer, MS, Labrique, A, Lee, NR, Lima, AÂM, Mahopo, TC, Maleta, K, Manandhar, DS, Manji, KP, Martorell, R, Mazumder, S, Mduma, E, Mohan, VR, Moore, SE, Ntozini, R, Nyathi, ME, Olortegui, MP, Ouédraogo, CT, Petri, WA, Premkumar, PS, Prentice, AM, Rahman, N, Ramirez-Zea, M, Sachdev, HS, Sadiq, K, Sarkar, R, Sarmin, M, Saville, NM, Shaikh, S, Shrestha, BP, Shrestha, SK, Soares, AM, Sonko, B, Stein, AD, Svensen, E |
| المصدر: | Nature , 621 (7979) pp. 568-576. (2023) |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2023 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | Ki Child Growth Consortium |
| الوصف: | Growth faltering in children (low length for age or low weight for length) during the first 1,000 days of life (from conception to 2 years of age) influences short-term and long-term health and survival 1,2. Interventions such as nutritional supplementation during pregnancy and the postnatal period could help prevent growth faltering, but programmatic action has been insufficient to eliminate the high burden of stunting and wasting in low- and middle-income countries. Identification of age windows and population subgroups on which to focus will benefit future preventive efforts. Here we use a population intervention effects analysis of 33 longitudinal cohorts (83,671 children, 662,763 measurements) and 30 separate exposures to show that improving maternal anthropometry and child condition at birth accounted for population increases in length-for-age z-scores of up to 0.40 and weight-for-length z-scores of up to 0.15 by 24 months of age. Boys had consistently higher risk of all forms of growth faltering than girls. Early postnatal growth faltering predisposed children to subsequent and persistent growth faltering. Children with multiple growth deficits exhibited higher mortality rates from birth to 2 years of age than children without growth deficits (hazard ratios 1.9 to 8.7). The importance of prenatal causes and severe consequences for children who experienced early growth faltering support a focus on pre-conception and pregnancy as a key opportunity for new preventive interventions. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://discovery.ucl.ac.uk/id/eprint/10177617/1/s41586-023-06501-x.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10177617Test/ |
| الإتاحة: | https://discovery.ucl.ac.uk/id/eprint/10177617/1/s41586-023-06501-x.pdfTest https://discovery.ucl.ac.uk/id/eprint/10177617Test/ |
| حقوق: | open |
| رقم الانضمام: | edsbas.398458F7 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |