التفاصيل البيبلوغرافية
| العنوان: |
A double-blind placebo-controlled trial of omeprazole on urinary pH in healthy subjects |
| المؤلفون: |
Osther, P J, Rasmussen, L, Pedersen, S A |
| المصدر: |
Osther , P J , Rasmussen , L & Pedersen , S A 1992 , ' A double-blind placebo-controlled trial of omeprazole on urinary pH in healthy subjects ' , International Urology and Nephrology , vol. 24 , no. 3 , pp. 229-31 . |
| سنة النشر: |
1992 |
| المجموعة: |
University of Southern Denmark: Research Output / Syddansk Universitet |
| مصطلحات موضوعية: |
Adult, Double-Blind Method, Humans, Hydrogen-Ion Concentration, Male, Omeprazole, Urine |
| الوصف: |
Urinary pH is related to urinary calculus formation as well as urinary infection. Omeprazole is an effective inhibitor of gastric acid secretion through inhibition of the parietal cell H+K+ATPase. In this study we have evaluated a possible effect of omeprazole on urine acidification. Ten healthy male subjects took placebo and omeprazole, 40 mg o.m., for 10 days in a double-blind placebo-controlled trial. Morning fasting urinary pH was measured on day 10 of each treatment course using a pH meter. No effect of omeprazole on urinary pH could be demonstrated. It is thus unlikely that it is necessary to take omeprazole treatment into consideration in stone screening. As omeprazole did not affect urinary pH, no urological side effects related to changes in urinary pH can be expected. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
https://portal.findresearcher.sdu.dk/da/publications/4cab33ed-5036-4032-895f-b45996c750e1Test |
| الإتاحة: |
https://portal.findresearcher.sdu.dk/da/publications/4cab33ed-5036-4032-895f-b45996c750e1Test |
| حقوق: |
info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: |
edsbas.393D0864 |
| قاعدة البيانات: |
BASE |
