دورية أكاديمية
Longitudinal changes in patient-ventilator asynchronies and respiratory system mechanics before and after tracheostomy
| العنوان: | Longitudinal changes in patient-ventilator asynchronies and respiratory system mechanics before and after tracheostomy |
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| المؤلفون: | Enrico Lena, José Aquino-Esperanza, Josefina López-Aguilar, Rudys Magrans, Candelaria de Haro, Leonardo Sarlabous, Neus López, Jaume Montanyà, Montserrat Rué, Robert M Kacmarek, Umberto Lucangelo, Rafael Fernández, Paolo Pelosi, Lluís Blanch |
| المساهمون: | Lena, Enrico, Aquino-Esperanza, José, López-Aguilar, Josefina, Magrans, Rudy, de Haro, Candelaria, Sarlabous, Leonardo, López, Neu, Montanyà, Jaume, Rué, Montserrat, M Kacmarek, Robert, Lucangelo, Umberto, Fernández, Rafael, Pelosi, Paolo, Blanch, Lluís |
| سنة النشر: | 2021 |
| المجموعة: | Università degli studi di Trieste: ArTS (Archivio della ricerca di Trieste) |
| مصطلحات موضوعية: | Adult, Human, Lung, Pilot Project, Prospective Studie, Respiration, Artificial, Respiratory Mechanic, Tracheostomy, Ventilators, Mechanical |
| الوصف: | Background: This was a pilot study to analyze the effects of tracheostomy on patient-ventilator asynchronies and respiratory system mechanics. Data were extracted from an ongoing prospective, real-world database that stores continuous output from ventilators and bedside monitors. Twenty adult subjects were on mechanical ventilation and were tracheostomized during an ICU stay: 55% were admitted to the ICU for respiratory failure and 35% for neurologic conditions; the median duration of mechanical ventilation before tracheostomy was 12 d; and the median duration of mechanical ventilation was 16 d. Methods: We compared patient-ventilator asynchronies (the overall asynchrony index and the rates of specific asynchronies) and respiratory system mechanics (respiratory-system compliance and airway resistance) during the 24 h before tracheostomy versus the 24 h after tracheostomy. We analyzed possible differences in these variables among the subjects who underwent surgical versus percutaneous tracheostomy. To compare longitudinal changes in the variables, we used linear mixed-effects models for repeated measures along time in different observation periods. A total of 920 h of mechanical ventilation were analyzed. Results: Respiratory mechanics and asynchronies did not differ significantly between the 24-h periods before and after tracheostomy: Compliance of the respiratory system median (IQR) (47.9 [41.3 - 54.6] mL/cm H2O vs 47.6 [40.9 - 54.3] mL/cm H2O; P =.94), airway resistance (9.3 [7.5 - 11.1] cm H2O/L/s vs 7.0 [5.2 - 8.8] cm H2O/L/s; P =.07), asynchrony index (2.0% [1.1 - 3.6%] vs 4.1% [2.3 - 7.6%]; P =.09), ineffective expiratory efforts (0.9% [0.4 - 1.8%] vs 2.2% [1.0 - 4.4%]; P =.08), double cycling (0.5% [0.3 - 1.0%] vs 0.9% [0.5 - 1.9%]; P =.24), and percentage of air trapping (7.6% [4.2 - 13.8%] vs 10.6% [5.9 - 19.2%]; P =.43). No differences in respiratory mechanics or patient-ventilator asynchronies were observed between percutaneous and surgical procedures. Conclusions: Tracheostomy did not affect ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34230215; info:eu-repo/semantics/altIdentifier/wos/WOS:000686562000004; volume:66; issue:9; firstpage:1389; lastpage:1397; numberofpages:9; journal:RESPIRATORY CARE; http://hdl.handle.net/11368/2998651Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85113609965; http://rc.rcjournal.com/content/66/9/1389Test |
| DOI: | 10.4187/respcare.08824 |
| الإتاحة: | https://doi.org/10.4187/respcare.08824Test http://hdl.handle.net/11368/2998651Test http://rc.rcjournal.com/content/66/9/1389Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.3879F809 |
| قاعدة البيانات: | BASE |
| DOI: | 10.4187/respcare.08824 |
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