مراجعة
Exploring the Link between
| العنوان: | Exploring the Link between |
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| المؤلفون: | Sgamato, Costantino, Rocco, Alba, Compare, Debora, Priadko, Kateryna, Romano, Marco, Nardone, Gerardo |
| المصدر: | Antibiotics (Basel) ; ISSN:2079-6382 ; Volume:13 ; Issue:6 |
| بيانات النشر: | MDPI |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | H. pylori, gastric cancer, gastric microbiota |
| الوصف: | Gastric cancer (GC) still represents one of the leading causes of cancer-related mortality and is a major public health issue worldwide. Understanding the etiopathogenetic mechanisms behind GC development holds immense potential to revolutionize patients' treatment and prognosis. Within the complex web of genetic predispositions and environmental factors, the connection between Helicobacter pylori (H. pylori) and gastric microbiota emerges as a focus of intense research investigation. According to the most recent hypotheses, H. pylori triggers inflammatory responses and molecular alterations in gastric mucosa, while non-Helicobacter microbiota modulates disease progression. In this review, we analyze the current state of the literature on the relationship between H. pylori and non-Helicobacter gastric microbiota in gastric carcinogenesis, highlighting the mechanisms by which microecological dysbiosis can contribute to the malignant transformation of the mucosa. |
| نوع الوثيقة: | review article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.3390/antibiotics13060484Test; https://pubmed.ncbi.nlm.nih.gov/38927151Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11201017Test/ |
| DOI: | 10.3390/antibiotics13060484 |
| الإتاحة: | https://doi.org/10.3390/antibiotics13060484Test https://pubmed.ncbi.nlm.nih.gov/38927151Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11201017Test/ |
| رقم الانضمام: | edsbas.37DBB075 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/antibiotics13060484 |
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