التفاصيل البيبلوغرافية
| العنوان: |
LETTER TO EDITOR Maternal Prenatal Smoking and Offspring Emotional Problems: No Moderating Effect of Maternal |
| المؤلفون: |
Or Child -httlpr Genotype, Lot M. Geels, Maria M. Groen-blokhuis, Catharina E. M. Van Beijsterveldt, Jacqueline M. Vink, Christel M. Middeldorp, Meike Bartels, Kelly A. Nelson, Patricia E. Huizenga, Gareth E. Davies, Dorret I. Boomsma |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
http://www.tweelingenregister.org/2012/Geels_AJMG_2012.pdfTest. |
| سنة النشر: |
2012 |
| المجموعة: |
CiteSeerX |
| الوصف: |
In a recent article, Cents et al. [2012] demonstrated a novel interaction effect of a polymorphism in the serotonin transporter gene (5-HTTLPR) and maternal prenatal smoking on offspring emotional (internalizing) problems at age 3 in a sample of 1,529 Dutch mother–child dyads. The 5-HTTLPR polymorphism has previously been shown to moderate effects of stressful life-events and childhood maltreatment on depression [Karg et al., 2011]. Cents et al. [2012] extended those findings to the period of fetal life using maternal prenatal smoking as the environmental risk factor, and offspring emotional problems at age 3 as the outcomemeasure. Cents et al. [2012] did not find a significant main effect of the 5-HTTLPR genotype or maternal prenatal smoking on offspring emotional problems, but detected an interaction effect. Having the short allele of the 5-HTTLPR polymorphism in combination with maternal smoking during pregnancy was associated with |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.464.8738Test; http://www.tweelingenregister.org/2012/Geels_AJMG_2012.pdfTest |
| الإتاحة: |
http://www.tweelingenregister.org/2012/Geels_AJMG_2012.pdfTest |
| حقوق: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.364274AB |
| قاعدة البيانات: |
BASE |
