دورية أكاديمية
Association between habitual sleep duration/quality and appetite markers in individuals with obesity
| العنوان: | Association between habitual sleep duration/quality and appetite markers in individuals with obesity |
|---|---|
| المؤلفون: | Nymo, Siren, Kleppe, Malin M., Coutinho, Silvia R., Rehfeld, Jens F., Kulseng, Bård, Martins, Catia |
| المصدر: | Nymo , S , Kleppe , M M , Coutinho , S R , Rehfeld , J F , Kulseng , B & Martins , C 2021 , ' Association between habitual sleep duration/quality and appetite markers in individuals with obesity ' , Physiology and Behavior , vol. 232 , 113345 . https://doi.org/10.1016/j.physbeh.2021.113345Test |
| سنة النشر: | 2021 |
| المجموعة: | University of Copenhagen: Research / Forskning ved Københavns Universitet |
| مصطلحات موضوعية: | Active ghrelin, Active GLP-1, CCK, Desire to eat, Hunger, Total PYY |
| الوصف: | Study Objectives: To assess if habitual sleep duration/quality was associated with appetite in individuals with obesity, and if the association was modulated by sex. Methods: Sleep duration/quality was measured with Pittsburgh Sleep Quality Index score in 95 healthy adults with obesity (BMI: 36.6 ± 4.2 kg/m 2 ). Subjective feelings of appetite were assessed using visual analogue scales, and plasma concentrations of active ghrelin, total peptide YY, active glucagon-like peptide 1, cholecystokinin (CCK) and insulin were measured in fasting and every 30 min up to 2.5 h after a meal. Results: No significant associations were found between sleep duration, or overall quality, and appetite in all participants. However, a worse sleep efficiency was associated with lower postprandial CCK, a shorter habitual sleep was associated with lower postprandial desire to eat and a lower daytime dysfunction was associated with higher prospective food consumption in fasting (P<0.05, for all). In males, a shorter habitual sleep duration and a worse subjective sleep quality were associated with increased basal and postprandial active ghrelin (P<0.05, P<0.01, P<0.01 and P<0.05, respectively). Also, a shorter habitual sleep was associated with lower basal and postprandial insulin (P<0.05 for both) and a worse overall sleep quality with lower postprandial insulin (P<0.05). In females, a worse overall sleep quality was associated with lower postprandial active ghrelin (P<0.05), and short habitual sleep with higher postprandial insulin (P<0.05). Conclusion: A worse habitual sleep efficiency is associated with blunted postprandial CCK secretion in individuals with obesity. The association between habitual sleep duration/quality and insulin and active ghrelin seems to be modulated by sex, but more studies are needed to confirm these findings. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1016/j.physbeh.2021.113345 |
| الإتاحة: | https://doi.org/10.1016/j.physbeh.2021.113345Test https://curis.ku.dk/portal/da/publications/association-between-habitual-sleep-durationquality-and-appetite-markers-in-individuals-with-obesityTest(e1244276-e0b0-4ce0-82ec-d1f27097ab83).html https://curis.ku.dk/ws/files/285881266/1_s2.0_S0031938421000378_main.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.357CB38B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.physbeh.2021.113345 |
|---|