التفاصيل البيبلوغرافية
| العنوان: |
Changes in cardiovascular health and white matter integrity with aerobic exercise, cognitive and combined training in physically inactive healthy late-middle-aged adults: the “Projecte Moviment” randomized controlled trial |
| المؤلفون: |
Roig-Coll, Francesca, Castells-Sánchez, Alba, Monté-Rubio, Gemma, Dacosta-Aguayo, Rosalía, Lamonja-Vicente, Noemí, Torán-Monserrat, Pere, Pere, Guillem, García-Molina, Alberto, Tormos, José Maria, Alzamora, Maria Teresa, Stavros, Dimitriadis, Sánchez-Ceron, Marta, Via, Marc, Erickson, Kirk I., Mataró, Maria |
| المساهمون: |
Ministerio de Economía y Competitividad, ICREA, Institución Catalana de Investigación y Estudios Avanzados, Ayudas para la formación de profesorado universitario, Ayudas para la contratación de personal investigador, Universitat de Barcelona |
| المصدر: |
European Journal of Applied Physiology ; ISSN 1439-6319 1439-6327 |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Physiology (medical), Public Health, Environmental and Occupational Health, Orthopedics and Sports Medicine, General Medicine, Physiology |
| الوصف: |
Introduction This is a 12-weeks randomized controlled trial examining the effects of aerobic exercise (AE), computerized cognitive training (CCT) and their combination (COMB). We aim to investigate their impact on cardiovascular health and white matter (WM) integrity and how they contribute to the cognitive benefits. Methods 109 participants were recruited and 82 (62% female; age = 58.38 ± 5.47) finished the intervention with > 80% adherence. We report changes in cardiovascular risk factors and WM integrity (fractional anisotropy (FA); mean diffusivity (MD)), how they might be related to changes in physical activity, age and sex, and their potential role as mediators in cognitive improvements. Results A decrease in BMI (SMD = − 0.32, p = 0.039), waist circumference (SMD = − 0.42, p = 0.003) and diastolic blood pressure (DBP) (SMD = − 0.42, p = 0.006) in the AE group and a decrease in BMI (SMD = − 0.34, p = 0.031) and DBP (SMD = − 0.32, p = 0.034) in the COMB group compared to the waitlist control group was observed. We also found decreased global MD in the CCT group (SMD = − 0.34; p = 0.032) and significant intervention-related changes in FA and MD in the frontal and temporal lobes in the COMB group. Conclusions We found changes in anthropometric measures that suggest initial benefits on cardiovascular health after only 12 weeks of AE and changes in WM microstructure in the CCT and COMB groups. These results add evidence of the clinical relevance of lifestyle interventions and the potential benefits when combining them. Clinical Trial Registration ClinicalTrials.gov NCT031123900. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1007/s00421-023-05319-9 |
| DOI: |
10.1007/s00421-023-05319-9.pdf |
| DOI: |
10.1007/s00421-023-05319-9/fulltext.html |
| الإتاحة: |
https://doi.org/10.1007/s00421-023-05319-9Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.34F879A6 |
| قاعدة البيانات: |
BASE |
