دورية أكاديمية
Ex-vivo effects of intrapulmonary percussive ventilation on sputum rheological properties.
| العنوان: | Ex-vivo effects of intrapulmonary percussive ventilation on sputum rheological properties. |
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| المؤلفون: | Wiame, Nicolas, Robert de Saint-Vincent, Matthieu, Audag, Nicolas, Aubriot, Anne-Sophie, Penelle, Morgane, Reychler, Gregory, Patarin, Jeremy, Poncin, William |
| المساهمون: | UCL - SSS/IREC/LUNS - Pôle pneumologie, ORL (airways) et dermatologie (skin), UCL - (SLuc) Service de pneumologie, UCL - (SLuc) Centre de référence pour la mucoviscidose |
| المصدر: | Respiratory physiology & neurobiology, Vol. 316, p. 104125 [1-7] (2023) |
| بيانات النشر: | Elsevier Science |
| سنة النشر: | 2023 |
| المجموعة: | DIAL@USL-B (Université Saint-Louis, Bruxelles) |
| مصطلحات موضوعية: | Adult, Humans, Sputum, Percussion, Lung, Respiration, Airway clearance techniques, Intrapulmonary percussive ventilation, Rheology, Viscoelasticity |
| الوصف: | Intrapulmonary percussive ventilation (IPV) has been postulated to enhance mucociliary clearance by improving tracheobronchial sputum rheological properties. The IPV effects on linear (viscoelasticity) and non-linear (flowing) rheological properties of 40 sputum samples collected from 19 patients with muco-obstructive lung diseases were investigated ex-vivo. Each sputum sample was split into 4 aliquots. These aliquots were independently placed in a circuit connected on one side to an IPV device and on the other side to a lung model that simulated spontaneous adult breaths. IPV was superimposed on simulated breathing. Three aliquots were exposed to a different IPV setting, modifying either percussion frequency or amplitude (4Â Hz-200Â L/min, 10Â Hz-200Â L/min, 10Â Hz-140Â L/min). One aliquot was only exposed to breathing (IPV was switched off, control condition). Each aliquot underwent 5Â min of the pre-fixed mechanical stimulation before being recollected to proceed to rheological analysis. Neither percussion frequencies nor amplitudes had a significant impact on any sputum rheological properties studied. These results need to be confirmed in vivo. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1569-9048 1878-1519 |
| العلاقة: | boreal:284536; http://hdl.handle.net/2078.1/284536Test; info:pmid/37516288; urn:ISSN:1569-9048; urn:EISSN:1878-1519 |
| DOI: | 10.1016/j.resp.2023.104125 |
| الإتاحة: | https://doi.org/10.1016/j.resp.2023.104125Test http://hdl.handle.net/2078.1/284536Test |
| حقوق: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.34AB8295 |
| قاعدة البيانات: | BASE |
| تدمد: | 15699048 18781519 |
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| DOI: | 10.1016/j.resp.2023.104125 |