دورية أكاديمية
A case of febrile infection-related epilepsy syndrome (FIRES) in young adult: still a diagnostic and therapeutic challenge.
| العنوان: | A case of febrile infection-related epilepsy syndrome (FIRES) in young adult: still a diagnostic and therapeutic challenge. |
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| المؤلفون: | Acampora, Roberto, Quiroga Subirana, Pablo, Durante, Luana, Tonziello, Rossella, Aversano, Giuseppina, Lieto, Maria, Ripa, Patrizia, Mazzaferro, Maria Pia |
| سنة النشر: | 2022 |
| المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
| مصطلحات موضوعية: | Antiepileptic drugs (AED), Epilepsy, FIRES, Immunoglobulin, NORSE, Drug Resistant Epilepsy, Encephalitis, Epileptic Syndromes, Humans, Immune System Diseases, Seizures, Status Epilepticus, Young Adult |
| الوصف: | A new onset of status epilepticus in a previously healthy adult preceded by a recent minor febrile infection represents a diagnostic and therapeutic challenge in clinical practice. Considering the broad spectrum of epileptic encephalopathies caused by autoimmune mechanisms, differential diagnosis for new-onset refractory status epilepticus (NORSE) should include febrile infection-related epilepsy syndrome (FIRES), in order to not underestimate the underlying etiological condition triggering epilepsy in non-epileptic patients (Hon et al. in Recent Pat Inflamm Allergy Drug Discov 12:128-135, 2018). We report a case of acute encephalopathy with refractory seizures after a febrile illness (FIRES) in a young adult with complete remission of symptoms as well as dramatic improvement of EEG abnormalities following intravenous immunoglobulin and proper antiepileptic medications. We conducted an extensive workup including lumbar puncture, blood tests, EEG serial monitoring, MRI brain, total body CT scan, and PET brain with FDG to shed light on the etiology of the disease. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1590-3478 |
| العلاقة: | http://hdl.handle.net/10668/20385Test; PMC9064715; https://link.springer.com/content/pdf/10.1007/s10072-022-06106-8.pdfTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064715/pdfTest |
| DOI: | 10.1007/s10072-022-06106-8 |
| DOI: | 10.1007/s10072-022-06106-8.pdf |
| الإتاحة: | https://doi.org/10.1007/s10072-022-06106-8Test http://hdl.handle.net/10668/20385Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064715/pdfTest |
| حقوق: | open access |
| رقم الانضمام: | edsbas.313A643C |
| قاعدة البيانات: | BASE |
| تدمد: | 15903478 |
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| DOI: | 10.1007/s10072-022-06106-8 |