دورية أكاديمية
Incidence, clinical characteristics, and outcome after unexpected cardiac arrest among critically ill adults with COVID-19: insight from the multicenter prospective ACICOVID-19 registry
| العنوان: | Incidence, clinical characteristics, and outcome after unexpected cardiac arrest among critically ill adults with COVID-19: insight from the multicenter prospective ACICOVID-19 registry |
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| المؤلفون: | Chelly, Jonathan, Plantefève, Gaetan, Kamel, Toufik, Bruel, Cédric, Nseir, Saad, Lai, Christopher, Cirillo, Giulia, Skripkina, Elena, Ehrminger, Sébastien, Berdaguer-Ferrari, Fernando-Daniel, Le Marec, Julien, Paul, Marine, Autret, Aurélie, Deye, Nicolas |
| المساهمون: | Centre Hospitalier Intercommunal Toulon-La Seyne sur Mer - Hôpital Sainte-Musse, Centre Hospitalier Victor Dupouy, Centre Hospitalier Régional d'Orléans (CHRO), Centre for Research in Epidemiology and Statistics, Conservatoire National des Arts et Métiers CNAM (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre hospitalier Saint-Joseph Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 (UGSF), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Université Paris-Saclay, Groupe Hospitalier Sud Ile-de-France (GHSIF), CHU Henri Mondor Créteil, Grand Hôpital de l'Est Francilien (GHEF), Hôpital Nord Franche-Comté Hôpital de Trévenans (HNFC), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU), Centre Hospitalier de Versailles André Mignot (CHV), Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, ACICOVID-19 study group: Jean-Michel Arnal, Julio Badie, Audrey Berric, Jennifer Brunet, Thibault Bertrand, Dorothée Carpentier, Karim Chaoui, Anaïs Chapelle, Riad Chelha, Gaëlle Corno, Cédric Daubin, Richard Descamps, Alexandre Demoule, Stéphanie Deryckere, Stephane-Yannis Donati, Laurent Ducros, Nathalie Embriaco, Nicolas Engrand, Camille Foucault, Sean Anthony Freeman, Santiago Freita Ramos, Arnaud Galbois, Aude Garnero, Cyrille Geay, Laurent Guérin, Vivien Hong Tuan Ha, Thomas Hullin, Sébastien Jochmans, Michel Kaidomar, Charlotte Kelway, Marie Labruyere, Romaric Larcher, Stéphane Legriel, Maxime Leloup, Olivier Lesieur, Isabelle Malissin, Sandie Mazerand, Bruno Mégarbane, Marie-Anne Mélone, Edouard Menoret, Matthieu Metzelard, Nicolas Mongardon, Ly Van Phack Vong, Romain Persichini, Nicolas Pichon, Santiago Picos Gil, Jean-Pierre Quenot, Damien Roux, David Schnell, Florian Sigaud, Clement Suply, Benjamin Sztrymf, Nicolas Terzi, Didier Thevenin, Sebastian Voicu |
| المصدر: | ISSN: 2110-5820 ; Annals of Intensive Care ; https://hal.science/hal-03427527Test ; Annals of Intensive Care, 2021, 11 (1), pp.155. ⟨10.1186/s13613-021-00945-y⟩. |
| بيانات النشر: | HAL CCSD SpringerOpen |
| سنة النشر: | 2021 |
| المجموعة: | LillOA (HAL Lille Open Archive, Université de Lille) |
| مصطلحات موضوعية: | COVID-19, In-hospital cardiac arrest, Intensive care unit, SARS-CoV-2, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Abstract Background Initial reports have described the poor outcome of unexpected cardiac arrest (CA) in intensive care unit (ICU) among COVID-19 patients in China and the USA. However, there are scarce data on characteristics and outcomes of such CA patients in Europe. Methods Prospective registry in 35 French ICUs, including all in-ICU CA in COVID-19 adult patients with cardiopulmonary resuscitation (CPR) attempt. Favorable outcome was defined as modified Rankin scale ranging from 0 to 3 at day 90 after CA. Results Among the 2425 COVID-19 patients admitted to ICU from March to June 2020, 186 (8%) experienced in-ICU CA, of whom 146/186 (78%) received CPR. Among these 146 patients, 117 (80%) had sustained return of spontaneous circulation, 102 (70%) died in the ICU, including 48 dying within the first day after CA occurrence and 21 after withdrawal of life-sustaining therapy. Most of CA were non-shockable rhythm (90%). At CA occurrence, 132 patients (90%) were mechanically ventilated, 83 (57%) received vasopressors and 75 (51%) had almost three organ failures. Thirty patients (21%) had a favorable outcome. Sepsis-related organ failure assessment score > 9 before CA occurrence was the single parameter constantly associated with unfavorable outcome in multivariate analysis. Conclusions In-ICU CA incidence remains high among a large multicenter cohort of French critically ill adults with COVID-19. However, 21% of patients with CPR attempt remained alive at 3 months with good functional status. This contrasts with other recent reports showing poor outcome in such patients. Trial registration : This study was retrospectively registered in ClinicalTrials.gov (NTC04373759) in April 2020 ( https://www.clinicaltrials.gov/ct2/show/NCT04373759?term=acicovid&draw=2&rank=1Test ). |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34773516; hal-03427527; https://hal.science/hal-03427527Test; https://hal.science/hal-03427527/documentTest; https://hal.science/hal-03427527/file/2021%20Chelly%20et%20al.,%20Incidence.pdfTest; PUBMED: 34773516; PUBMEDCENTRAL: PMC8590126 |
| DOI: | 10.1186/s13613-021-00945-y |
| الإتاحة: | https://doi.org/10.1186/s13613-021-00945-yTest https://hal.science/hal-03427527Test https://hal.science/hal-03427527/documentTest https://hal.science/hal-03427527/file/2021%20Chelly%20et%20al.,%20Incidence.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.2FC5A168 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13613-021-00945-y |
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