دورية أكاديمية
Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis
العنوان: | Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis |
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المؤلفون: | Foulquier, Sebastien, Boehm, Michael, Schmieder, Roland, Sleight, Peter, Teo, Koon, Yusuf, Salim, Schumacher, Helmut, Unger, Thomas |
المصدر: | Foulquier , S , Boehm , M , Schmieder , R , Sleight , P , Teo , K , Yusuf , S , Schumacher , H & Unger , T 2014 , ' Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis ' , Journal of Hypertension , vol. 32 , no. 6 , pp. 1334-1341 . https://doi.org/10.1097/HJH.0000000000000154Test |
سنة النشر: | 2014 |
المجموعة: | Maastricht University Research Publications |
مصطلحات موضوعية: | angiotensin receptor blocker, hypertension, myocardial infarction, telmisartan |
الوصف: | Background:In the Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease, all patients were at high cardiovascular risk, and a substantial proportion were hypertensive. We performed a post-hoc analysis to explore the hypothesis that telmisartan has a differential action in hypertensive vs. nonhypertensive patients.Methods:The primary four-fold endpoint (composite of cardiovascular death, myocardial infarction (MI), stroke, or hospitalization for heart failure), the secondary three-fold endpoint (cardiovascular death, MI, and stroke), the individual components, new onset of left ventricular hypertrophy (LVH), and new onset of albuminuria were analyzed.Results:There was no evidence for a significantly differential treatment effect of telmisartan in hypertensive and nonhypertensive patients for any endpoints, although the occurrence of the secondary three-fold endpoint was significantly lower in the telmisartan group (13.0%) compared with placebo (15.0%, P |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
DOI: | 10.1097/HJH.0000000000000154 |
الإتاحة: | https://doi.org/10.1097/HJH.0000000000000154Test https://cris.maastrichtuniversity.nl/en/publications/39996bda-d8e0-45e8-828e-63ec09c66d20Test https://cris.maastrichtuniversity.nl/ws/files/72937915/foulquier_2014_impact_of_telmisartan_on_cardiovascular.pdfTest |
حقوق: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.2C01C744 |
قاعدة البيانات: | BASE |
DOI: | 10.1097/HJH.0000000000000154 |
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