دورية أكاديمية
Effect of estradiol on oocyte development
| العنوان: | Effect of estradiol on oocyte development |
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| المؤلفون: | Bianco, Katherine, Mahutte, Neal G., Arici, Aydin, Sakkas, Denny, Taylor, Hugh S. |
| المصدر: | International Journal of Gynecology & Obstetrics ; volume 104, issue 3, page 230-232 ; ISSN 0020-7292 1879-3479 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2008 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Objective To determine whether elevated serum estradiol (E 2 ) concentrations in oocyte donors affect assisted reproduction outcome. Method In a retrospective cohort study of 58 consecutive oocyte donation cycles, donors were stratified into 2 groups according to E 2 concentration, group 1 (n = 32; E 2 ≤ 2000 pg/mL [range 456–2000 pg/mL]) and group 2 (n = 27; E 2 > 2000 pg/mL [range, 2062–6957 pg/mL]). Data were analyzed using the t test and χ 2 test. Results Donors in group 1 produced significantly less oocytes than donors in group 2 (19.3 ± 1.7 vs 12.0 ± 1.4; P < 0.001), and recipients of oocytes from group 1 had significantly fewer numbers of embryos available for transfer (10.4 ± 1.1 vs 6.4 ± 0.8; P = 0.003). However, the mean number (3.3) of embryos transferred and the pregnancy rate were the same in both groups. Conclusion Elevated estradiol concentration in oocyte donors did not affect pregnancy outcome, suggesting that estradiol levels in donors do not affect oocyte development. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1016/j.ijgo.2008.10.015 |
| الإتاحة: | https://doi.org/10.1016/j.ijgo.2008.10.015Test http://api.elsevier.com/content/article/PII:S0020729208004864?httpAccept=text/plainTest http://api.elsevier.com/content/article/PII:S0020729208004864?httpAccept=text/xmlTest |
| حقوق: | http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: | edsbas.2A288BF0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.ijgo.2008.10.015 |
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