دورية أكاديمية

Systems of conductive skin for power transfer in clinical applications

التفاصيل البيبلوغرافية
العنوان: Systems of conductive skin for power transfer in clinical applications
المؤلفون: Kourouklis, Andreas P., Kaemmel, Julius, Wu, Xi, Potapov, Evgenij, Cesarovic, Nikola, id_orcid:0 000-0001-6744-2928, Ferrari, Aldo, Starck, Christoph, Falk, Volkmar, id_orcid:0 000-0002-7911-8620, Mazza, Edoardo
المصدر: European Biophysics Journal, 51 (2)
بيانات النشر: Springer
سنة النشر: 2022
المجموعة: ETH Zürich Research Collection
مصطلحات موضوعية: Left ventricular assist devices (LVAD), Cardiac implantable electronic device (CIED), Driveline infections (DLIs), Foreign body reaction (FBR), Surface topography, Biofilm
الوصف: The primary aim of this article is to review the clinical challenges related to the supply of power in implanted left ventricular assist devices (LVADs) by means of transcutaneous drivelines. In effect of that, we present the preventive measures and post-operative protocols that are regularly employed to address the leading problem of driveline infections. Due to the lack of reliable wireless solutions for power transfer in LVADs, the development of new driveline configurations remains at the forefront of different strategies that aim to power LVADs in a less destructive manner. To this end, skin damage and breach formation around transcutaneous LVAD drivelines represent key challenges before improving the current standard of care. For this reason, we assess recent strategies on the surface functionalization of LVAD drivelines, which aim to limit the incidence of driveline infection by directing the responses of the skin tissue. Moreover, we propose a class of power transfer systems that could leverage the ability of skin tissue to effectively heal short diameter wounds. In this direction, we employed a novel method to generate thin conductive wires of controllable surface topography with the potential to minimize skin disruption and eliminate the problem of driveline infections. Our initial results suggest the viability of the small diameter wires for the investigation of new power transfer systems for LVADs. Overall, this review uniquely compiles a diverse number of topics with the aim to instigate new research ventures on the design of power transfer systems for IMDs, and specifically LVADs. ; ISSN:0175-7571 ; ISSN:1432-1017
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/application/pdf
اللغة: English
العلاقة: info:eu-repo/semantics/altIdentifier/wos/000692449800001; info:eu-repo/grantAgreement/SNF/Projekte MINT/179012; http://hdl.handle.net/20.500.11850/505294Test
DOI: 10.3929/ethz-b-000505294
الإتاحة: https://doi.org/20.500.11850/505294Test
https://doi.org/10.3929/ethz-b-000505294Test
https://doi.org/10.1007/s00249-021-01568-8Test
https://hdl.handle.net/20.500.11850/505294Test
حقوق: info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0Test/ ; Creative Commons Attribution 4.0 International
رقم الانضمام: edsbas.29131DCF
قاعدة البيانات: BASE