دورية أكاديمية
Evaluating the Safety of Simultaneous Intracranial Electroencephalography and Functional Magnetic Resonance Imaging Acquisition Using a 3 Tesla Magnetic Resonance Imaging Scanner
| العنوان: | Evaluating the Safety of Simultaneous Intracranial Electroencephalography and Functional Magnetic Resonance Imaging Acquisition Using a 3 Tesla Magnetic Resonance Imaging Scanner |
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| المؤلفون: | Fujita, Yuya, Khoo, Hui Ming, Hirayama, Miki, Kawahara, Masaaki, Koyama, Yoshihiro, Tarewaki, Hiroyuki, Arisawa, Atsuko, Yanagisawa, Takufumi, Tani, Naoki, Oshino, Satoru, Lemieux, Louis, Kishima, Haruhiko |
| المصدر: | Frontiers in Neuroscience , 16 , Article 921922. (2022) |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2022 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | 3 tesla, MRI, depth electrode, epilepsy, fMRI, safety, simultaneous intracranial EEG-fMRI, subdural electrode |
| الوصف: | Background: The unsurpassed sensitivity of intracranial electroencephalography (icEEG) and the growing interest in understanding human brain networks and ongoing activities in health and disease have make the simultaneous icEEG and functional magnetic resonance imaging acquisition (icEEG-fMRI) an attractive investigation tool. However, safety remains a crucial consideration, particularly due to the impact of the specific characteristics of icEEG and MRI technologies that were safe when used separately but may risk health when combined. Using a clinical 3-T scanner with body transmit and head-receive coils, we assessed the safety and feasibility of our icEEG-fMRI protocol. Methods: Using platinum and platinum-iridium grid and depth electrodes implanted in a custom-made acrylic-gel phantom, we assessed safety by focusing on three factors. First, we measured radio frequency (RF)-induced heating of the electrodes during fast spin echo (FSE, as a control) and the three sequences in our icEEG-fMRI protocol. Heating was evaluated with electrodes placed orthogonal or parallel to the static magnetic field. Using the configuration with the greatest heating observed, we then measured the total heating induced in our protocol, which is a continuous 70-min icEEG-fMRI session comprising localizer, echo-planar imaging (EPI), and magnetization-prepared rapid gradient-echo sequences. Second, we measured the gradient switching-induced voltage using configurations mimicking electrode implantation in the frontal and temporal lobes. Third, we assessed the gradient switching-induced electrode movement by direct visual detection and image analyses. Results: On average, RF-induced local heating on the icEEG electrode contacts tested were greater in the orthogonal than parallel configuration, with a maximum increase of 0.2°C during EPI and 1.9°C during FSE. The total local heating was below the 1°C safety limit across all contacts tested during the 70-min icEEG-fMRI session. The induced voltage was within the 100-mV safety limit ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://discovery.ucl.ac.uk/id/eprint/10152473/1/Lemieux_fnins-16-921922.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10152473Test/ |
| الإتاحة: | https://discovery.ucl.ac.uk/id/eprint/10152473/1/Lemieux_fnins-16-921922.pdfTest https://discovery.ucl.ac.uk/id/eprint/10152473Test/ |
| حقوق: | open |
| رقم الانضمام: | edsbas.26294C54 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |