دورية أكاديمية
Influence of fractional flow reserve on grafts patency. Systematic review and patient-level meta-analysis
| العنوان: | Influence of fractional flow reserve on grafts patency. Systematic review and patient-level meta-analysis |
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| المؤلفون: | G. Toth G., Collet C., Langhoff Thuesen A., Mizukami T., Casselman F., Riber L. P., Van Praet F., Junker A., Nagumo S., De Bruyne B., Okkels Jensen L., Barbato E. |
| المساهمون: | G. Toth, G., Collet, C., Langhoff Thuesen, A., Mizukami, T., Casselman, F., Riber, L. P., Van Praet, F., Junker, A., Nagumo, S., De Bruyne, B., Okkels Jensen, L., Barbato, E. |
| بيانات النشر: | John Wiley and Sons Inc |
| سنة النشر: | 2022 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | coronary artery bypass surgery, fractional flow reserve, graft patency |
| الوصف: | Objective: To investigate the impact of invasive functional guidance for coronary artery bypass graft surgery (CABG) on graft failure. Background: Data on the impact of fractional flow reserve (FFR) in guiding CABG are still limited. Methods: Systematic review and individual patient data meta-analysis were performed. Primary objective was the risk of graft failure, stratified by FFR. Risk estimates are reported as odds ratios (ORs) derived from the aggregated data using random-effects models. Individual patient data were analyzed using mixed effect model to assess relationship between FFR and graft failure. This meta-analysis is registered in PROSPERO (CRD42020180444). Results: Four prospective studies comprising 503 patients referred for CABG, with 1471 coronaries, assessed by FFR were included. Graft status was available for 1039 conduits at median of 12.0 [IQR 6.6; 12.0] months. Risk of graft failure was higher in vessels with preserved FFR (OR 5.74, 95% CI 1.71–19.29). Every 0.10 FFR units decrease in the coronaries was associated with 56% risk reduction of graft failure (OR 0.44, 95% CI 0.34 to 0.59). FFR cut-off to predict graft failure was 0.79. Conclusion: Surgical grafting of coronaries with functionally nonsignificant stenoses was associated with higher risk of graft failure. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34233071; info:eu-repo/semantics/altIdentifier/wos/WOS:000670365700001; volume:99; issue:3; firstpage:730; lastpage:735; numberofpages:6; journal:CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS; https://hdl.handle.net/11573/1699870Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85109733169 |
| DOI: | 10.1002/ccd.29864 |
| الإتاحة: | https://doi.org/10.1002/ccd.29864Test https://hdl.handle.net/11573/1699870Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.259FCAB9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/ccd.29864 |
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