دورية أكاديمية
Cutaneous Involvement in Waldenström's Macroglobulinaemia.
| العنوان: | Cutaneous Involvement in Waldenström's Macroglobulinaemia. |
|---|---|
| المؤلفون: | Stien, Sarah, Durot, Eric, Durlach, Anne, Beylot-Barry, Marie, Adamski, Henri, Beltraminelli, Helmut, Bohelay, Gérôme, Carlotti, Agnès, Carpentier, Olivier, Cornillet, Pascale, Dubois, Romain, Franck, Nathalie, Husson, Bérengère, Laroche, Liliane, Maubec, Eve, le Clech, Christian, Machet, Laurent, Ortonne, Nicolas, Ram-Wolff, Caroline, Vergier, Béatrice, Grange, Florent |
| المصدر: | Stien, Sarah; Durot, Eric; Durlach, Anne; Beylot-Barry, Marie; Adamski, Henri; Beltraminelli, Helmut; Bohelay, Gérôme; Carlotti, Agnès; Carpentier, Olivier; Cornillet, Pascale; Dubois, Romain; Franck, Nathalie; Husson, Bérengère; Laroche, Liliane; Maubec, Eve; le Clech, Christian; Machet, Laurent; Ortonne, Nicolas; Ram-Wolff, Caroline; Vergier, Béatrice; . (2020). Cutaneous Involvement in Waldenström's Macroglobulinaemia. Acta dermato-venereologica, 100(15), adv00225. Forum for Nordic Dermato-Venereology 10.2340/00015555-3535 |
| بيانات النشر: | Forum for Nordic Dermato-Venereology |
| سنة النشر: | 2020 |
| المجموعة: | BORIS (Bern Open Repository and Information System, University of Bern) |
| مصطلحات موضوعية: | 610 Medicine & health |
| الوصف: | Cutaneous involvement in Waldenström's macroglobulinaemia (WM) has been poorly characterized. To describe this involvement, a retrospective study of 19 patients with WM and cutaneous involvement of tumour B cells was performed. Twelve patients (group 1) had lymphoplasmacytic, non-transformed cutaneous proliferation, while in 7 cases (group 2) cutaneous involvement corresponded to histological transformation. In group 1, skin involvement was inaugural in 6 cases. The lesions were infiltrated plaques (83%), papules (25%) and tumours (42%). Four patients had a similar clinical picture (purplish, bilateral and symmetrical infiltration on the face). MYD88 L265P mutation was detected in the skin biopsy in all 6 cases tested. The 3-year specific survival rate was 88%. In group 2, cutaneous transformation occurred during the follow-up of the WM (71%). Lesions presented as ulcerated tumours (86%) of the trunk (57%) and lower limbs (57%). The 3-year specific survival rate was 22%. Skin involvement in WM has distinctive characteristics (e.g. clinical, histological, immunohistochemical, MYD88 L265P mutation). |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://boris.unibe.ch/149478Test/ |
| الإتاحة: | https://doi.org/10.2340/00015555-3535Test https://boris.unibe.ch/149478/1/5788.pdfTest https://boris.unibe.ch/149478Test/ |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.23CDCDDF |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |