دورية أكاديمية
Prescription appropriateness of anti-diabetes drugs in elderly patients hospitalized in a clinical setting: evidence from the REPOSI Register
| العنوان: | Prescription appropriateness of anti-diabetes drugs in elderly patients hospitalized in a clinical setting: evidence from the REPOSI Register |
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| المؤلفون: | Elena Succurro, Alessio Novella, Alessandro Nobili, Federica Giofrè, Franco Arturi, Angela Sciacqua, Francesco Andreozzi, Antonello Pietrangelo, Giorgio Sesti, Francesco Perticone, Francesco Violi, Salvatore Corrao, Alessandra Marengoni, Mauro Tettamanti, Luca Pasina, Carlotta Franchi, Gabriella Miglio, Ilaria Ardoino, Silvia Cantiero, Domenico Prisco, Elena Silvestri, Giacomo Emmi, Alessandra Bettiol, Irene Mattioli, Matteo Mazzetti, Gianni Biolo, Michela Zanetti, Giacomo Bartelloni, Michele Zaccari, Massimiliano Chiuch, Ilaria Martini, Matteo Pirro, Graziana Lupattelli, Vanessa Bianconi, Riccardo Alcidi, Alessia Giotta, Massimo R Mannarino, Domenico Girelli, Fabiana Busti, Giacomo Marchi, Mario Barbagallo, Ligia Dominguez, Vincenza Beneduce, Federica Cacioppo, Giuseppe Natoli, Salvatore Mularo, Massimo Raspanti, Christiano Argano, Federica Cavallaro, Marco Zoli, Giuseppe Orio, Eleonora Magnolfi, Giovanni Serafini, Mattia Brunori, Ilaria Lazzari, Angelo Simili, Giovanna Fabio, Margherita Migone De Amicis, Giacomo Luca, Natalia Scaramellini, Valeria Stefano, Simona Leoni, Sonia Seghezzi, Alessandra Danuto Di Mauro, Diletta Maira, Marta Mancarella, Tiziano Lucchi, Marta Clerici, Giulia Bonini, Federica Conti, Silvia Prolo, Maddalena Fabrizi, Miriana Martelengo, Giulia Vigani, Paola Nicolini, Antonio Sabatino, Emanuela Miceli, Martina Pisati, Lavinia Pitotti, Valentina Antoci, Ginevra Cambiè, Roberto Pontremoli, Valentina Beccati, Giulia Nobili, Giovanna Leoncini, Jacopo Alberto, Federico Cattaneo, Luigi Anastasio, Lucia Sofia, Maria Carbone, Francesco Cipollone, Ilaria Rossi, Emanuele Valeriani, Damiano D'Ardes, Alessia Cipollone, Lucia Esposito, Simona Sestili, Ermanno Angelucci, Gerardo Mancuso, Daniela Calipari, Mosè Bartone, Roberto Manetti, Marta Sircana, Maria Berria, Alessandro Delitala, Maurizio Muscaritoli, Alessio Molfino, Enrico Petrillo, Antonella Giorgi, Christian Gracin, Giovanni Imbimbo, Giuseppe Romanelli, Andrea Volpini, Daniela Lucente, Francesca Manzoni, Annalisa Pirozzi, Alberto Zucchelli, Thelma Geneletti, Antonio Picardi, Giuseppe Bellelli, Maurizio Corsi, Cesare Antonucci, Chiara Sidoli, Giulia Principato, Alessandra Bonfanti, Hajnalka Szabo, Paolo Mazzola, Andrea Piazzoli, Bruno Tassone, Antonio Brucato, Teresa De Falco, Enrica Negro, Martino Brenna, Lucia Trotta, Fabrizio Fabris, Irene Bertozzi, Giulia Bogoni, Tancredi Prandini, Francesco Ratti, Chiara Zurlo, Lorenzo Cerruti, Elisabetta Cosi, Elisa Reni, Roberto Manfredini, Benedetta Boari, Alfredo De Giorgi, Ruana Tiseo, Caterina Savriè, Fabio Fabbian, Giuseppe Paolisso, Claudia Catalano, Irene Meo, Carlo Sabbà, Patrizia Suppressa, Giovanni Michele De Vincenzo, Alessio Comitangelo, Emanuele Amoruso, Carlo Custodero, Giuseppe Re, Ivano Barnaba, Andrea Schilardi, Luigi Fenoglio, Andrea Falcetta, Salvatore D'Aniano, Silvia Tiraboschi, Annalisa Cespiati, Giovanna Oberti, Giordano Sigon, Felice Cinque, Lucia Colavolpe, Jaqueline Currà, Francesca Alletto, Alessandra Danuta Di Mauro, Gianpaolo Benzoni, Flora Peyvandi, Raffaella Rossio, Giulia Colombo, Pasquale Agosti, Erica Pagliaro, Eleonora Semproni, Ciro Canetta, Valter Monzani, Valeria Savojardo, Giuliana Ceriani, Christian Folli, Tiziana Tognin, Francesco Purrello, Antonino Pino, Salvatore Piro, Renzo Rozzini, Lina Falanga, Stefano Boffelli, Camillo Ferrandina, Francesca Mazzeo, Elena Spazzini, Giulia Cono, Giulia Cesaroni, Ludovica Perri, Luigina Guasti, Francesca Rotunno, Luana Castiglioni, Andrea Maresca, Alessandro Squizzato, Leonardo Campiotti, Alessandra Grossi, Francesco Dentali, Veronica Behnke, Maria Perticone, Raffaele Maio, Aleandra Scozzafava, Valentino Condoleo, Elvira Clausi, Giuseppe Armentaro, Alberto Panza, Vincenzo Stanghellini, Eugenio Ruggeri, Sara Vecchio, Ilaria Benzoni, Salvatore Minisola, Luciano Colangelo, Mirella Cilli, Giancarlo Labbadia, Jessica Pepe, Pietro Castellino, Luca Zanoli, Agostino Gaudio, Anastasia Xourafa, Concetta Spichetti, Serena Torre, Alfio Gennaro, Alberto Ballestrero, Fabio Ferrando, Roberta Gonella, Domenico Cerminara, Paolo Setti, Chiara Traversa, Camilla Scarsi, Giuseppe Famularo, Patrizia Tarsitani, Tiziana Morretti, Andrea Aglitti, Stefano Giacco, Davide Firinu, Giulia Costanzo, Salvatore Chessa, Giuseppe Montalto, Anna Licata, Angelo Rizzo, Francesco Corica, Giorgio Basile, Antonino Catalano, Federica Bellone, Concetto Principato, Angelo Cocuzza, Patrizia Mecocci, Carmelinda Ruggiero, Virginia Boccardi, Tiziana Meschi, Andrea Ticinesi, Antonio Nouvenne, Mario Pirisi, Daniele Sola, Mattia Bellan, Roberto Quadri, Erica Larovere, Marco Novelli, Emilio Simeone, Rosa Scurti, Fabio Tolloso, Roberto Tarquini, Alice Valoriani, Silvia Dolenti, Giulia Vannini, Riccardo Volpi, Pietro Bocchi, Alessandro Vignali, Sergio Harari, Chiara Lonati, Federico Napoli, Italia Aiello, Teresa Salvatore, Lucio Monaco, Carmen Ricozzi, Francesca Coviello, Christian Catalini, Alberto Pilotto, Ilaria Indiano, Federica Gandolfo, Davide Gonella, Ranuccio Nuti, Roberto Valenti, Martina Ruvio, Silvia Cappelli, Alberto Palazzuoli, Vittorio Durante, Daniela Tirotta, Giovanna Eusebi, Moreno Tresoldi, Enrica Bozzolo, Sarah Damanti, Massimo Porta, Miriam Gino, Bianca Pari, Edoardo Pace. |
| المساهمون: | Succurro, Elena, Novella, Alessio, Nobili, Alessandro, Giofrè, Federica, Arturi, Franco, Sciacqua, Angela, Andreozzi, Francesco, Pietrangelo, Antonello, Sesti, Giorgio, Perticone, Francesco, Violi, Francesco, Corrao, Salvatore, Marengoni, Alessandra, Tettamanti, Mauro, Pasina, Luca, Franchi, Carlotta, Miglio, Gabriella, Ardoino, Ilaria, Cantiero, Silvia, Prisco, Domenico, Silvestri, Elena, Emmi, Giacomo, Bettiol, Alessandra, Mattioli, Irene, Mazzetti, Matteo, Biolo, Gianni, Zanetti, Michela, Bartelloni, Giacomo, Zaccari, Michele, Chiuch, Massimiliano, Martini, Ilaria, Pirro, Matteo, Lupattelli, Graziana, Bianconi, Vanessa, Alcidi, Riccardo, Giotta, Alessia, R Mannarino, Massimo, Girelli, Domenico, Busti, Fabiana, Marchi, Giacomo, Barbagallo, Mario, Dominguez, Ligia, Beneduce, Vincenza, Cacioppo, Federica, Natoli, Giuseppe, Mularo, Salvatore, Raspanti, Massimo, Argano, Christiano, Cavallaro, Federica, Zoli, Marco, Orio, Giuseppe, Magnolfi, Eleonora, Serafini, Giovanni, Brunori, Mattia, Lazzari, Ilaria, Simili, Angelo, Fabio, Giovanna, Migone De Amicis, Margherita, Luca, Giacomo, Scaramellini, Natalia, Stefano, Valeria, Leoni, Simona, Seghezzi, Sonia, Danuto Di Mauro, Alessandra, Maira, Diletta, Mancarella, Marta, Lucchi, Tiziano, Clerici, Marta, Bonini, Giulia, Conti, Federica, Prolo, Silvia, Fabrizi, Maddalena, Martelengo, Miriana, Vigani, Giulia, Nicolini, Paola, Sabatino, Antonio, Miceli, Emanuela, Pisati, Martina, Pitotti, Lavinia, Antoci, Valentina, Cambiè, Ginevra, Pontremoli, Roberto, Beccati, Valentina, Nobili, Giulia, Leoncini, Giovanna, Alberto, Jacopo, Cattaneo, Federico, Anastasio, Luigi, Sofia, Lucia, Carbone, Maria, Cipollone, Francesco, Rossi, Ilaria, Valeriani, Emanuele, D'Ardes, Damiano, Cipollone, Alessia, Esposito, Lucia |
| سنة النشر: | 2023 |
| المجموعة: | Università degli Studi di Ferrara: CINECA IRIS |
| مصطلحات موضوعية: | Anti-diabetes drugs, Diabetes, Elderly people, Hospitalized patients, Prescription appropriateness |
| الوصف: | Diabetes is an increasing global health burden with the highest prevalence (24.0%) observed in elderly people. Older diabetic adults have a greater risk of hospitalization and several geriatric syndromes than older nondiabetic adults. For these conditions, special care is required in prescribing therapies including anti- diabetes drugs. Aim of this study was to evaluate the appropriateness and the adherence to safety recommendations in the prescriptions of glucose-lowering drugs in hospitalized elderly patients with diabetes. Data for this cross-sectional study were obtained from the REgistro POliterapie-Società Italiana Medicina Interna (REPOSI) that collected clinical information on patients aged ≥ 65 years acutely admitted to Italian internal medicine and geriatric non-intensive care units (ICU) from 2010 up to 2019. Prescription appropriateness was assessed according to the 2019 AGS Beers Criteria and anti-diabetes drug data sheets.Among 5349 patients, 1624 (30.3%) had diagnosis of type 2 diabetes. At admission, 37.7% of diabetic patients received treatment with metformin, 37.3% insulin therapy, 16.4% sulfonylureas, and 11.4% glinides. Surprisingly, only 3.1% of diabetic patients were treated with new classes of anti- diabetes drugs. According to prescription criteria, at admission 15.4% of patients treated with metformin and 2.6% with sulfonylureas received inappropriately these treatments. At discharge, the inappropriateness of metformin therapy decreased (10.2%, P < 0.0001). According to Beers criteria, the inappropriate prescriptions of sulfonylureas raised to 29% both at admission and at discharge. This study shows a poor adherence to current guidelines on diabetes management in hospitalized elderly people with a high prevalence of inappropriate use of sulfonylureas according to the Beers criteria. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/36964858; info:eu-repo/semantics/altIdentifier/wos/WOS:000958739700002; volume:18; issue:4; firstpage:1049; lastpage:1063; numberofpages:15; journal:INTERNAL AND EMERGENCY MEDICINE; https://hdl.handle.net/11392/2517070Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85164263510; https://link.springer.com/article/10.1007/s11739-023-03254-3Test |
| DOI: | 10.1007/s11739-023-03254-3 |
| الإتاحة: | https://doi.org/10.1007/s11739-023-03254-3Test https://hdl.handle.net/11392/2517070Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.2360352 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s11739-023-03254-3 |
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