دورية أكاديمية
Optimizing Acellular Dermal Matrix Integration in Heterologous Breast Reconstructive Surgery: Surgical Tips and Post-Operative Management
| العنوان: | Optimizing Acellular Dermal Matrix Integration in Heterologous Breast Reconstructive Surgery: Surgical Tips and Post-Operative Management |
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| المؤلفون: | Caputo G., Scarabosio A., Di Filippo J., Contessi Negrini F., Albanese R., Mura S., Parodi P. C. |
| المساهمون: | Caputo, G., Scarabosio, A., Di Filippo, J., Contessi Negrini, F., Albanese, R., Mura, S., Parodi, P. C. |
| سنة النشر: | 2023 |
| المجموعة: | Università degli Studi di Udine: CINECA IRIS |
| مصطلحات موضوعية: | ADM integration, breast reconstruction, breast surgery, dermal matrix, heterologous reconstruction, implant-based reconstruction, prepectoral reconstruction ADM |
| الوصف: | Background and Objective: Prepectoral implant placement in breast reconstruction is currently a must-have in the portfolios of breast surgeons. The introduction of new tools and conservative mastectomies is a game changer in this field. The prepectoral plane usually goes hand-in-hand with the ADM wrapping of the implant. It is a cell-free dermal matrix comprising a structurally integrated basement membrane complex and an extracellular matrix. The literature reports that ADMs may be useful, but proper patient selection, surgical placement, and post-operative management are essential to unlock the potential of this tool, as these factors contribute to the proper integration of the matrix with surrounding tissues. Materials and Methods: A total of 245 prepectoral breast reconstructions with prostheses or expanders and ADMs were performed in our institution between 2016 and 2022. A retrospective study was carried out to record patient characteristics, risk factors, surgical procedures, reconstructive processes, and complications. Based on our experience, we developed a meticulous reconstruction protocol in order to optimize surgical practice and lower complication rates. The DTI and two-stage reconstruction were compared. Results: Seroma formation was the most frequent early complication (less than 90 days after surgery) that we observed; however, the majority were drained in outpatient settings and healed rapidly. Secondary healing of wounds, which required a few more weeks of dressing, represented the second most frequent early complication (10.61%). Rippling was the most common late complication, particularly in DTI patients. After comparing the DTI and two-stage reconstruction, no statistically significant increase in complications was found. Conclusions: The weakness of prepectoral breast reconstruction is poor matrix integration, which leads to seroma and other complications. ADM acts like a graft; it requires firm and healthy tissues to set in. In order to do so, there are three key steps to follow: (1) ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:001036449900001; volume:59; issue:7; firstpage:1231; journal:MEDICINA; https://hdl.handle.net/11390/1260064Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85165983664 |
| DOI: | 10.3390/medicina59071231 |
| الإتاحة: | https://doi.org/10.3390/medicina59071231Test https://hdl.handle.net/11390/1260064Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.20C7E61C |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/medicina59071231 |
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