دورية أكاديمية

Blood Cadmium Level Is a Marker of Cancer Risk in Men

التفاصيل البيبلوغرافية
العنوان: Blood Cadmium Level Is a Marker of Cancer Risk in Men
المؤلفون: Derkacz, Róża, Marciniak, Wojciech, Jakubowska, Anna, Scott, Rodney J., Lubiński, Jan, Baszuk, Piotr, Wysokińska, Monika, Chrzanowska, Natalia, Lener, Marcin, Huzarski, Tomasz, Gronwald, Jacek, Dębniak, Tadeusz, Cybulski, Cezary
المساهمون: The University of Newcastle. College of Health, Medicine & Wellbeing, School of Biomedical Sciences and Pharmacy
بيانات النشر: MDPI AG
سنة النشر: 2024
المجموعة: NOVA: The University of Newcastle Research Online (Australia)
مصطلحات موضوعية: cadmium, cancer risk, prospective study, men
الوصف: Cadmium (Cd) is a known carcinogen, but its impact on cancer risk at lower concentrations is poorly understood. Previous studies on Cd and cancer risk in men show inconsistent results, prompting further investigation. A prospective cohort study involving 2956 men was conducted. Blood Cd levels were measured, and participants were followed for 78 months to assess cancer incidence. Men with high blood Cd levels (>0.71 µg/L) had a significantly increased risk of cancer compared to those with low levels (<0.19 µg/L) (HR 3.42, p < 0.001), particularly among non-smokers (HR 3.74, p = 0.003), individuals aged < 60 years (HR 2.79, p = 0.017), and ≥60 (HR 4.63, p = 0.004). The influence of smoking on cancer risk based on Cd levels was not significant in this study. Blood Cd levels may influence cancer risk in men, emphasizing the importance of minimizing Cd exposure to reduce risk. Confirmation of these results in other populations is essential for effective preventive measures against Cd-related cancers.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2072-6643
العلاقة: Nutrients Vol. 16, Issue 9, no. 1309; http://hdl.handle.net/1959.13/1504115Test; uon:55448
الإتاحة: http://hdl.handle.net/1959.13/1504115Test
حقوق: X
رقم الانضمام: edsbas.2028440A
قاعدة البيانات: BASE