دورية أكاديمية
Photon-Counting Detector CT for Kidney Stone Detection in Excretory Phase CT-Comparison Between Virtual Non-contrast and Virtual Non-iodine Reconstructions in a 3D Printed Kidney Phantom
| العنوان: | Photon-Counting Detector CT for Kidney Stone Detection in Excretory Phase CT-Comparison Between Virtual Non-contrast and Virtual Non-iodine Reconstructions in a 3D Printed Kidney Phantom |
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| المؤلفون: | Breiding, Philipe S, Gomollon, Ana Maria Turrion, Martini, Katharina, Nakhostin, Dominik, Alkadhi, Hatem, Euler, André |
| المصدر: | Breiding, Philipe S; Gomollon, Ana Maria Turrion; Martini, Katharina; Nakhostin, Dominik; Alkadhi, Hatem; Euler, André (2024). Photon-Counting Detector CT for Kidney Stone Detection in Excretory Phase CT-Comparison Between Virtual Non-contrast and Virtual Non-iodine Reconstructions in a 3D Printed Kidney Phantom. Academic Radiology:Epub ahead of print. |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2024 |
| المجموعة: | University of Zurich (UZH): ZORA (Zurich Open Repository and Archive |
| مصطلحات موضوعية: | Clinic for Diagnostic and Interventional Radiology, 610 Medicine & health |
| الوصف: | RATIONALE AND OBJECTIVES To evaluate and compare the effectiveness of contrast media subtraction and kidney stone detection between a virtual non-iodine reconstruction algorithm (VNI; PureCalcium) and a virtual non-contrast (VNC) algorithm in excretory phase photon-counting detector computed tomography (PCD-CT), using a 3D printed kidney phantom under various tube voltages and radiation doses. MATERIALS AND METHODS A 3D-printed kidney phantom, holding Calcium Oxalate (CaOx) and uric acid stones within contrast-enhanced calyces, was created. The calyx density mirrored the average density observed in 200 excretory phase patients (916 HU at 110 kV). Imaging was conducted on a clinical dual-source PCD-CT at 120 kV and 140 kV, with radiation doses set at 5, 10, and 15 mGy. VNI and VNC algorithms were applied. Two blinded readers evaluated the image quality, along with the degree of contrast media and kidney stone subtraction, using visual scales. Krippendorff's alpha was calculated to determine inter-reader agreement, and the Chi-squared test was employed for comparing ordinal data. RESULTS Reader 2 rated overall image quality higher for VNI than VNC (4.90 vs. 4.00; P < .05), while Reader 1 found no significant difference (4.96 vs. 5.00; P > .05). Substantial agreement was observed between readers for contrast media subtraction in both VNC and VNI (Krippendorff's alpha range: 0.628-0.748). Incomplete contrast media subtraction occurred more frequently with VNI for both readers (Reader 1: 29% vs. 15%; P < .05; Reader 2: 24% vs. 20%; P > .05). Uric acid and smaller stones (<5 mm) were more likely to be subtracted than CaOx and larger stones in both VNC and VNI. Overall, a higher rate of stone subtraction was noted with VNI compared to VNC (Reader 1: 22% vs. 16%; Reader 2: 25% vs. 10%; P < .05). Neither radiation dose nor tube voltage significantly influenced stone subtraction (P > .05). CONCLUSION VNC demonstrated greater accuracy than VNI for contrast media subtraction and kidney stone visibility. ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1076-6332 |
| العلاقة: | https://www.zora.uzh.ch/id/eprint/259490/1/ZORA_259490.pdfTest; info:pmid/38641450; urn:issn:1076-6332 |
| DOI: | 10.5167/uzh-259490 |
| DOI: | 10.1016/j.acra.2024.04.002 |
| الإتاحة: | https://doi.org/10.5167/uzh-259490Test https://doi.org/10.1016/j.acra.2024.04.002Test https://www.zora.uzh.ch/id/eprint/259490Test/ https://www.zora.uzh.ch/id/eprint/259490/1/ZORA_259490.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess ; Creative Commons: Attribution 4.0 International (CC BY 4.0) ; http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.1F6E15D5 |
| قاعدة البيانات: | BASE |
| تدمد: | 10766332 |
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| DOI: | 10.5167/uzh-259490 |